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  2. Apr 8, 2020 · In this literature review, the causative agent, pathogenesis and immune responses, epidemiology, diagnosis, treatment and management of the disease, control and preventions strategies are all reviewed. Keywords: 2019-nCoV, COVID-19, Outbreak, SARS-CoV-2, Novel coronavirus. Go to:

    • Harapan Harapan, Naoya Itoh, Amanda Yufika, Wira Winardi, Synat Keam, Haypheng Te, Dewi Megawati, Zi...
    • 2020
    • Research Question
    • Study Design
    • Ethics
    • Eligibility Criteria
    • Information Sources
    • Search
    • Study Selection
    • Data Collection Process
    • Data Items
    • Quality Assessment in Individual Reviews

    This overview’s primary objective was to summarize and critically appraise systematic reviews that assessed any type of primary clinical data from patients infected with SARS-CoV-2. Our research question was purposefully broad because we wanted to analyze as many systematic reviews as possible that were available early following the COVID-19 outbre...

    We conducted an overview of systematic reviews. The idea for this overview originated in a protocol for a systematic review submitted to PROSPERO (CRD42020170623), which indicated a plan to conduct an overview. Overviews of systematic reviews use explicit and systematic methods for searching and identifying multiple systematic reviews addressing re...

    Approval of a research ethics committee was not necessary as the study analyzed only publicly available articles.

    Systematic reviews were included if they analyzed primary data from patients infected with SARS-CoV-2 as confirmed by RT-PCR or another pre-specified diagnostic technique. Eligible reviews covered all topics related to COVID-19 including, but not limited to, those that reported clinical symptoms, diagnostic methods, therapeutic interventions, labor...

    Nine databases were searched for eligible records published between December 1, 2019, and March 24, 2020: Cochrane Database of Systematic Reviews via Cochrane Library, PubMed, EMBASE, CINAHL (Cumulative Index to Nursing and Allied Health Literature), Web of Sciences, LILACS (Latin American and Caribbean Health Sciences Literature), PDQ-Evidence, WH...

    The comprehensive search strategy for each database is provided in Additional file 1 and was designed and conducted in collaboration with an information specialist. All retrieved records were primarily processed in EndNote, where duplicates were removed, and records were then imported into the Covidence platform . In addition to database searches, ...

    All searches, screening of titles and abstracts, and record selection, were performed independently by two investigators using the Covidence platform . Articles deemed potentially eligible were retrieved for full-text screening carried out independently by two investigators. Discrepancies at all stages were resolved by consensus. During the screeni...

    We custom designed a data extraction table for this study, which was piloted by two authors independently. Data extraction was performed independently by two authors. Conflicts were resolved by consensus or by consulting a third researcher.

    We extracted the following data: article identification data (authors’ name and journal of publication), search period, number of databases searched, population or settings considered, main results and outcomes observed, and number of participants. From Web of Science (Clarivate Analytics, Philadelphia, PA, USA), we extracted journal rank (quartile...

    Two researchers independently assessed the reviews’ quality using the “A MeaSurement Tool to Assess Systematic Reviews 2 (AMSTAR 2)”. We acknowledge that the AMSTAR 2 was created as “a critical appraisal tool for systematic reviews that include randomized or non-randomized studies of healthcare interventions, or both” . However, since AMSTAR 2 was ...

    • Israel Júnior Borges do Nascimento, Dónal P. O’Mathúna, Thilo Caspar von Groote, Hebatullah Mohamed ...
    • 2021
  3. 3 days ago · SARS-CoV-2 is a positive-sense single-stranded RNA virus. It is contagious in humans and is the cause of the coronavirus disease 2019 (COVID-19). Latest Research and Reviews. Prevalence of...

  4. Oct 29, 2021 · These papers highlight valuable research into the biology of coronavirus infection, its detection, treatment as well as into vaccine development and the epidemiology of the disease.

  5. The WHO COVID-19 Research Database was a resource created in response to the Public Health Emergency of International Concern (PHEIC). It contained citations with abstracts to scientific articles, reports, books, preprints, and clinical trials on COVID-19 and related literature.

  6. Jun 16, 2020 · The COVID-19 pandemic has resulted in unprecedented research worldwide. The impact on research in progress at the time of the pandemic, the importance and challenges of real-time pandemic...

  7. LitCovid is a unique web system for tracking the most recent publications and literature about the 2019 Coronavirus (2019-nCov,SARS-CoV-2, COVID-19) outbreak. LitCovid is the most comprehensive resource on the subject.

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