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Snowdrops are important source of anti-neurodegeneration compound “galanthamine” thanks to the traditional knowledge in which the extract has been used in folk medicine for neurological conditions (Ago et al., 2011).
Feb 19, 2021 · The Galanthus nivalis agglutinin (GNA) was identified and purified from the bulb of snowdrop (Van Damme et al., 1987). GNA is known to possess virucidal properties against human immunodeficiency virus (HIV) at the EC 50 = 0.12 ± 0.07 μg/ml to 4.7 ± 3 μg/ml ( Balzarini et al., 2004 ).
- Chee Kei Kong, Liang Ee Low, Wei Sheng Siew, Wei Hsum Yap, Kooi Yeong Khaw, Long Chiau Ming, Andrei ...
- 10.3389/fphar.2020.552453
- 2021
- Front Pharmacol. 2020; 11: 552453.
Apr 28, 2023 · The most studied Galanthus alkaloid, galanthamine, is a long-acting, selective, reversible, competitive inhibitor of AChE and an allosteric modulator of the neuronal nicotinic receptor for acetylcholine (ACh). Owing to its AChE inhibitory activity, galanthamine is used to treat certain stages of AD.
- 10.4103/jehp.jehp_451_22
- 2023
- J Educ Health Promot. 2023; 12: 128.
Sep 12, 2023 · Galanthus Nivalis, commonly known as the snowdrop, has attracted the attention of researchers and scientists worldwide due to its unique chemical composition and potential medicinal properties. 1. Alzheimer’s Disease Research: Galantamine, a compound found in snowdrops, has been extensively studied for its role in Alzheimer’s disease treatment.
Common snowdrops (Galanthus nivalis) are among the first spring blooms, decorating woodlands, meadows, and gardens with a carpet of white.
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Jul 27, 2018 · Although Galanthus nivalis L. (snowdrop) is known for the galanthamine content, used in the treatment of Alzheimer disease, the polyphenolic compounds of Amaryllidaceae species are less studied.
A solitary faintly scented early bloomer. Bell-shaped white flower, held on a slender pedicel. 6 tepals, three outer are white are white, oblong, entire, obtuse, 1.5-2 cm. Three inner segments are white with an apical green mark, entire, emarginate, cuneate, elliptic, shorter than outter 3 tepals.
