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6 days ago · Our synthesis commenced with α,β-unsaturated imine 31. An intermolecular hetero-Diels−Alder reaction using 1,1-dimethoxyethene 56 as the dienophile followed by hydrolysis generated lactam 57 ...
1 day ago · Read the latest articles of Chemical Engineering and Processing - Process Intensification at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
6 days ago · 2-Phenylindoles, as a special subset of indole compounds, stand out as some of the most promising candidates for drug development. To guide researchers toward developing new 2-phenylindole drugs in a more environmentally friendly and cost-effective manner, we have summarized and analyzed synthesis methods for 2-phenylindole over the past two decades. Our key findings are as follows: First ...
May 13, 2024 · Here, we report the α-alkylation of unprotected alanine and glycine by pyridinium salts using pyridoxal (PLP)-dependent threonine aldolases with a Rose Bengal photoredox catalyst. The strategy efficiently prepares various a -tertiary amino acids in a single chemical step as a single enantiomer.
May 1, 2024 · We herein report dehydrogenative synthesis of N-functionalized 2-aminophenols from cyclohexanones and amines. The developed reaction system enables incorporating amino and hydroxyl groups into aromatic rings in a one-shot fashion, which simplifies polyfunctionalized 2-aminophenol synthesis by circumventing issues associated with traditional ...
5 days ago · The field of reaction engineering is in a constant state of evolution, adapting to new technologies and the changing demands of process development on accelerated timelines. Recent advancements in laboratory automation, data-rich experimentation, and machine learning have revolutionized chemical synthesis research,
4 days ago · The study and understanding of the biomineralization process of magnetosomes can provide important guidance to the chemical synthesis of magnetosomes-like Fe 3 O 4 nanoparticles. Meanwhile, the in-depth investigations of bioinspired syntheses can in turn bring us closer to nature and reveal the mechanism of biomeralization in magnetotactic ...
