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  2. May 30, 2024 · A new variant of COVID-19, known as FLiRT, is now the most dominant strain in the U.S. This variant, which evolved from the omicron strain, is characterized by changes in its spike protein — the part of the virus that binds to host cells.

  3. Jun 7, 2024 · The FDA panel recommended the updated COVID vaccines target JN.1, the parent of all the FLiRT variants currently circulating. FDA adviser Dr. Melinda Wharton suggested that targeting the “trunk of the tree” would offer some protection against subvariants that may emerge.

  4. 6 days ago · “We know that the updated monovalent vaccine, which was designed for the XBB.1.5 variant, worked against JN.1, and I strongly suspect it will have some degree of activity against the FLiRT mutations as well,” Dr. Roberts says.

    • kathy.katella-cofrancesco@yale.edu
  5. Jun 9, 2024 · COVID fall vaccine will target JN.1. The dominant emergence of the KP.3 variant comes on the heels of an FDA panel meeting this week to discuss updates to a COVID vaccine for the fall.

  6. Jun 13, 2024 · These data included information on the circulation of SARS-CoV-2 virus variants, current vaccine effectiveness, human immunogenicity data of current vaccines against recently...

  7. Jun 5, 2024 · To identify variants, scientists map the genetic material of viruses (known as sequencing) and then look for differences between them to see if they have changed. Since 2020, SARS-CoV-2, the virus that causes COVID-19, has been spreading and changing globally.

  8. Jun 7, 2024 · The FDA told the advisory committee Wednesday that studies have shown that the currently available Covid-19 vaccines appear to be less effective against the variants that are now in...

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