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- Season 5 overviewSep 27, 2017-May 9, 201822 episodesSeason 5 episodes22. Homecoming May 9, 2018
- Olinsky is stabbed in prison; Woods looks to take down Voight once and for all.
- 21. Lealtad May 2, 2018
- Halstead and Atwater go under cover to prevent military-grade weapons from hitting the street.
- 20. Saved Apr 18, 2018
- Voight witnesses the kidnapping of a young woman with a mysterious connection to his past.
- 19. Revancha Apr 11, 2018
- Robberies lead to an unlikely individual; Voight confronts a witness in the Bingham investigation.
- 18. Ghosts Mar 21, 2018
- Upton tries to take down a meth ring spearheaded by a former contact.
- 17. Breaking Point Mar 14, 2018
- A prominent alderman who is known for his urban revitalization efforts is killed.
- 16. Profiles Mar 7, 2018
- A string of bombings is targeting members of the media; the team enlists firehouse 51 to help.
- 15. Sisterhood Feb 28, 2018
- Burgess begins to question if the men who attacked her sister truly paid for their actions.
- 14. Himno Feb 7, 2018
- A basketball star is found murdered after an anti-police rally; the team searches for the killer.
- 13. Persiguiendo monstruos Jan 31, 2018
- The team works with a visiting detective to put an end to a gang's brutal tactics.
- 12. Captive Jan 17, 2018
- The intelligence unit rallies to rescue Atwater when he disappears from a convicted felon's house.
- 11. Confidencial Jan 10, 2018
- Burgess works with her first criminal informant to track down a ruthless pimp.
- 10. Rabbit Hole Jan 3, 2018
- Halstead puts his career on the line to help solve a case; Voight discovers the mole in his unit.
- 9. Monster Dec 6, 2017
- The death of Judge Tommy Wells' daughter puts Intelligence on the track of a pill mill.
- 8. Política Nov 29, 2017
- One of Voight's friends is found passed out in his hotel room with a dead Ukranian girl.
- 7. Care Under Fire Nov 15, 2017
- Halstead goes under cover to stop an ex-military kidnapping crew from killing an innocent child.
- 6. Caídos Nov 8, 2017
- A family is killed, and the team searches for a drug dealer with a likely connection.
- 5. Home Oct 25, 2017
- A meth lab bust uncovers a scam in which children adopted from foreign countries are sold online.
- 4. Snitch Oct 18, 2017
- The investigation into a drug-related homicide is hampered by the neighborhood's no-snitch culture.
- 3. Promise Oct 11, 2017
- The investigation into an illegal immigrant's murder is stifled by the city's perception of police.
- 2. Lo que tienen los héroes Oct 4, 2017
- A patrol officer becomes a suspect when a van explodes during a Chicago street festival.
- 1. Reform Sep 27, 2017
- A young bystander is shot during a difficult operation; Chief Lugo reviews the shootout.