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Sep 3, 2023 · Cephalexin is a first-generation β-lactam antibiotic used in adults and pediatrics to treat various streptococcal and staphylococcal infections. This review aims to summarize and evaluate all the pharmacokinetic (PK) data on cephalexin by screening out all pertinent studies in human beings following the per oral (PO) route.
- 10.3390/antibiotics12091402
- 2023/09
- Antibiotics (Basel). 2023 Sep; 12(9): 1402.
Oct 1, 2020 · We conclude that cephalexin and cefadroxil have very good early bacteriological and clinical cures in uLUTIs due to non-extended-spectrum beta-lactamase-producing (ESBL) Enterobacteriaceae comparable to many traditionally first-line agents.
- Hien M. Nguyen, Christopher J. Graber
- 2020
Dec 1, 2012 · Synopsis: Cephalexin 2 is an orally active semisynthetic derivative of the cephalosporin nucleus (7-amino cephalosporanic acid) with a spectrum of activity against both Gram-positive and Gram-negative bacteria.
- T. M. Speight, R. N. Brogden, G. S. Avery
- 1972
May 5, 2017 · Key Points. Question. Does cephalexin plus trimethoprim-sulfamethoxazole yield higher clinical cure rates than cephalexin alone for treatment of patients with uncomplicated cellulitis? Findings.
- Gregory J. Moran, Anusha Krishnadasan, William R. Mower, Fredrick M. Abrahamian, Frank LoVecchio, Ma...
- 10.1001/jama.2017.5653
- 2017
- JAMA. 2017 May 23; 317(20): 2088-2096.
Feb 13, 2024 · Cefdinir and cephalexin are cephalosporin antibiotics commonly used in the treatment of urinary tract infections (UTIs). Their efficacy depends on achieving sufficient time with concentrations exceeding the minimum inhibitory concentration (MIC).
Aug 17, 2023 · Cephalexin is commonly utilized in the treatment of urinary tract infections, respiratory infections, otitis media, bone infections caused by Staphylococcus aureus or Proteus mirabilis, and skin and soft tissue infections primarily caused by S aureus or Streptococcus pyogenes.
May 3, 2022 · Intervention: HD PO cephalexin treatment guideline. All children treated for moderate cellulitis using the guideline received HD PO cephalexin at 90 mg/kg/day (a dose aimed at non-osteoarticular infections) divided in three doses (max 1.5 g/dose, 4.5 g/day).
