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- His research led to a study of disease prevention and the treatment of disease by vaccines and immune serums (a branch of medicine now called immunology). Other scientists recognized the importance of bacteria in agriculture and the dairy industry.
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Emil von Behring was a German bacteriologist who was one of the founders of immunology. In 1901 he received the first Nobel Prize for Physiology or Medicine for his work on serum therapy, particularly for its use in the treatment of diphtheria.
- The Editors of Encyclopaedia Britannica
Now you can better understand Behring's most important contribution to microbiology. While at the Institute for Hygiene, Behring began to study the interactions between blood...
- Upbringing and Education
- The Behring Family
- Family and Friends
- The Development of The Diphtheria-Therapeutic-Serum
- The Introduction of Serum Therapy
- The Marburg Years
- Scientific Contacts
- Active Protective Vaccination Against Diphtheria
- Tetanus Therapeutic Serum During World War I
- An Attempt to Develop A Therapeutic Method Against Tuberculosis
Emil Behring(1854-1917) was born on March 15, 1854 in Hansdorf, West Prussia, as the first child of the couple August and Auguste Behring. His father was a village school teacher, who during his first marriage had had four children and after the birth of Emil had another eight children. A talented pupil, Emil Behring was above all assisted by the v...
During his early years as a military doctor, Behring’s income was not sufficient for him to think about starting a family. Only in 1896, when he had a regular salary, did he marry the 20 year old Else Spinola. They went on a three-month honeymoon to the island of Capri. Else, born August 30, 1876 in Berlin, was the daughter of Werner Spinola, Admin...
On the list of his sons’ godfathers, it appears obvious who stood closest to Emil von Behring besides his family. His first son, Fritz, had the bacteriologist Friedrich Loeffler (1852-1915) and Behring’s friend and co-worker, Erich Wernicke as godfathers. The godfather of his third son, Hans, was the Prussian Under-Secretary of Education and Cultur...
Behring, who in the early 1890s became an assistant at the Institute for Infectious Diseases, headed by Robert Koch, started his studies with experiments on the development of a therapeutic serum. In 1890, together with his university friend Erich Wernicke, he had managed to develop the first effective therapeutic serum against diphtheria. At the s...
The first successful therapeutic serum treatment of a child suffering from diphtheria occurred in 1891. Until then more than 50,000 children in Germany died yearly of diphtheria. During the first few years, there was no successful breakthrough for this form of therapy, as the antitoxins were not sufficiently concentrated. Not until the development ...
Behring was given the opportunity to start a university career through one of the leading officers (Ministerialrat) of the Prussian Ministry of Education and Cultural Affairs, Friedrich Althoff (1839-1908), who wanted to improve the control of epidemics in Prussia by supporting bacteriological research. After a short period as professor at the Univ...
Behring belonged to a scientific discussion group called “The Marburg Circle” (das Marburger Kränzchen), whose other members were the zoologist Eugen Korschelt (1858-1946), the surgeon Paul Friedrich (1864-1916), the botanist Arthur Meyer (1850-1922), the physiologist Friedrich Schenk (1862-1916), the pathologist Carl August Beneke (1861-1945) and ...
The therapeutic serum developed by Behring prevented diphtheria for only a short period of time. In 1901, Behring, therefore, for the first time, used a diphtheria innoculation of bacteria with reduced virulence. With this active immunization he hoped to help the body also produce antitoxins. As a supporter of the humoral theory of immune response,...
In 1891, tetanus serum was introduced considerably more quickly in clinical practices than the diphtheria serum. The Agricultural Ministry supported research efforts to develop a therapeutic agent against tetanus to protect agriculturally valuable animals. The large amounts of serum required were obtained through the immunization of horses. However...
After Robert Koch had failed with his tuberculosis therapy in 1893, Behring began to search for an effective therapeutic agent against this disease. However, very soon, he had to admit that combating tuberculosis using a healing serum was not feasible. Therefore, he concentrated on working on a preventive vaccination, which, however, required preci...
Feb 28, 2017 · A century ago, Emil von Behring passed away. He was the first to be honored by the Nobel Prize for Medicine in 1901 for the successful therapy of diphtheria and tetanus, which he had developed from the bench to the bed. He also contributed to the foundation of immunology, since his therapy was based on passive immunization with specific antisera.
- Stefan H. E. Kaufmann
- 10.1128/mBio.00117-17
- 2017
- mBio. 2017 Jan-Feb; 8(1): e00117-17.
von Behring. His contribution included the development of histological stains that enabled him to identify mast cells. He defined the concepts of active immuniza-tion and devised methods for measuring the levels of specific antibody in serum after immunization. In the course of his studies he demonstrated that antibodies could be transmitted ...
Trained as a military surgeon, Emil von Behring later became interested in microbiology and received a position in the Berlin laboratory of Robert Koch (1843-1910). His work with Shibasaburo Kitasato (1852-1931) on diphtheria showed the efficacy of blood serum as a treatment.
Emil von Behring was born in Hansdorf in 1854 and received his education at the Army Medical College in Berlin, where he after some years in Posen, came to work closely with Robert Koch (Medicine Prize in 1905). von Behring primarily studied the tuberculosis and diphteria bacteria.
