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  2. Aug 7, 2023 · Clostridium botulinum produces botulinum toxin and causes botulism, a rare disease manifested as various clinical syndromes ranging from food poisoning, wound infection to infant botulism. The term is derived from Latin word botulus, meaning sausage, as poorly cooked sausages were formerly associated with food poisoning.

    • Aman Tiwari, Shivaraj Nagalli
    • 2023/08/07
  3. C. botulinum was first recognized and isolated in 1895 by Emile van Ermengem from home-cured ham implicated in a botulism outbreak. The isolate was originally named Bacillus botulinus, after the Latin word for sausage, botulus. ("Sausage poisoning" was a common problem in 18th- and 19th-century Germany, and was most likely caused by botulism.)

  4. May 8, 2023 · In 1917, the anaerobic bacilli were reclassified into the genus Clostridium (from the Greek word “Kloster,” meaning spindle shape) and was subsequently renamed to Clostridium botulinum . Georgina Burke was responsible for the letter designation of different serotypes in 1919 (BoNT/A and B) .

    • 10.1080/21505594.2023.2205251
    • 2023
    • Virulence. 2023; 14(1): 2205251.
  5. Sep 25, 2023 · Clostridium botulinum is a bacterium that produces dangerous toxins (botulinum toxins) under low-oxygen conditions. Botulinum toxins are one of the most lethal substances known. Botulinum toxins block nerve functions and can lead to respiratory and muscular paralysis.

  6. Aug 7, 2013 · Where is Clostridium botulinum Found? C. botulinum is prevalent in soil and marine sediments worldwide, most commonly as spores. These spores are found everywhere. While the spores are generally harmless, the danger can occur once the spores begin to grow out into active bacteria and produce neurotoxins.

  7. Clostridium botulinum is a Gram-positive, strict-anaerobic, motile, pleomorphic, catalase-negative, endospore-forming bacillus (rod) that is ubiquitously found in the soil. The endopores of C. botulinum are sub-terminally placed or located on the bacterium and they are oval in shape.

  8. Apr 18, 2024 · Botulism causes difficulty breathing, muscle paralysis, and even death. The toxin is made by Clostridium botulinum and sometimes Clostridium butyricum and Clostridium baratii bacteria (germs). These bacteria can produce the toxin in food, wounds, and the intestines of infants.

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