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1. www.erowid.org › archive › rhodiumThe Synthesis of Phencyclidine and Other 1 ... - Erowid

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   thesis of 1-phenylcyclohexylamine. The compound prepared by the alternate route (method F) was identi- cal in all respects with the one obtained prepared from Method F aC6"I NCO - CxCeH5 "2 VI phenylcyclohexene. Recently, Cristol, et ul., re- ported the isolation of the amine as its benzoyl deriva- tive via a modified Ritter reaction.

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3. webbook.nist.gov › cgi › cbookN-Phenylcyclohexylamine - NIST Chemistry WebBook

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   Feb 6, 2010 · IUPAC Standard InChI: InChI=1S/C12H17N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1,3-4,7-8,12-13H,2,5-6,9-10H2 Copy IUPAC Standard InChIKey: TXTHKGMZDDTZFD-UHFFFAOYSA-N ...

4. chem.libretexts.org › Bookshelves › Organic_Chemistry24.6: Synthesis of Amines - Chemistry LibreTexts

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   Alkylation is an efficient method for the synthesis of 3 o and 4 o amines. However, when 1 o and 2 o amines are alkylated a mixture of products is typically produced. When ammonia is reacted with an alkylhalide an monoalkylammonium salt is formed. RX + NH 3 → RNH 3+ + X -.

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   Are there any arylcyclohexamine analogues?

   • The only case series of other arylcyclohexamine analogues comes from the Swedish STRIDA project, which reported 59 cases of acute 3- and 4-MeO-PCP toxicity [ 101 ]; 86.4 % were male and the median age was 26 years.

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

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   Are arylcyclohexamines dissociative?

   • Policies and ethics Arylcyclohexamines (also known as arylcyclohexylamines) are a group of compounds that contain a cyclohexamine unit with an aryl moiety, typically a phenyl ring, attached to the same atom to which the amine group is linked (see Fig. 1). They all exhibit dissociative...

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

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   What are the clinical signs of methoxylated arylcyclohexamine use?

   • The most frequent clinical signs observed with methoxylated arylcyclohexamine use were akin to those observed with PCP, ketamine, and MXE use (see Table 7 ); altered conscious state (57.6 %), tachycardia (54.2 %), and hypertension (45.8 %) are the most commonly reported, while nystagmus was seen in 30.5 % of cases.

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

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   Does chronic use of arylcyclohexamines affect working memory?

   • The subsequent reduction in dopaminergic activity seen with chronic use of arylcyclohexamines also plays a role in decreased working memory function of the prefrontal cortex [ 226 ].

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

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6. chemistry.mdma.ch › hiveboard › rhodiumUse of PCA (1-phenylcyclohexylamine) as a precursor

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   Step 3: 1-phenylcyclohexylamine (PCA): To a cooled solution of 198 gm of KOH in 1 L of water was added 18 mL of bromine, and the solution further cooled to 7 C. 67.3 gm (0.331 mole) of 1-phenylcyclohexanecarboxamide was added at once, and the mixture held at 3-9 C for 90 min. with stirring. It was then extracted 3 times with 200 mL of ether ...

7. webbook.nist.gov › cgi › inchiN-Phenylcyclohexylamine - NIST Chemistry WebBook

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   • Phase Change Data
   • References
   • Notes

   Go To: Top, References, Notes Data compilation copyrightby the U.S. Secretary of Commerce on behalf of the U.S.A.All rights reserved. Data compiled by: Robert L. Brown and Stephen E. Stein

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   Go To: Top, Phase change data, Notes Data compilation copyrightby the U.S. Secretary of Commerce on behalf of the U.S.A.All rights reserved. Weast and Grasselli, 1989 CRC Handbook of Data on Organic Compounds, 2nd Editon, Weast,R.C and Grasselli, J.G., ed(s)., CRC Press, Inc., Boca Raton, FL, 1989, 1. [all data]

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   Go To: Top, Phase change data, References 1. Symbols used in this document: 2. Data from NIST Standard Reference Database 69:NIST Chemistry WebBook 3. The National Institute of Standards and Technology (NIST)uses its best efforts to deliver a high quality copy of theDatabase and to verify that the data contained therein havebeen selected on the bas...

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8. www.semanticscholar.org › paper › THE-SYNTHESIS-OFTHE SYNTHESIS OF PHENCYCLIDINE AND OTHER 1 ...

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   Various 1-arylcyclohexylamines were synthesized for evaluation as central nervous system depressants and tested for cataleptoid activity and antitonic extensor properties. Various 1-arylcyclohexylamines were synthesized for evaluation as central nervous system depressants. The compounds were prepared by several procedures. 1-(1-Phenylcyclohexyl)piperidine, the first compound of this type ...

9. link.springer.com › referenceworkentry › 10Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

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   Jan 1, 2016 · The first arylcyclohexamine to be described was 1-(1-phenylcyclohexyl) amine, in 1907, almost 50 years before the synthesis of PCP . Other analogues reported in the early 1950s included N-ethyl-1-phenylcyclohexylamine (PCE) and 1-(1-phenylcyclohexyl)morpholine (PCMo). While many were not explored further by their initial investigators, chemists ...