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  1. Dictionary
    Vi·cis·si·tude
    /vəˈsisəˌto͞od/

    noun

    • 1. a change of circumstances or fortune, typically one that is unwelcome or unpleasant: "her husband's sharp vicissitudes of fortune"
  2. The meaning of VICISSITUDE is the quality or state of being changeable : mutability. How to use vicissitude in a sentence. Changes and Vicissitude.

  3. noun. a variation in circumstances or fortune at different times in your life or in the development of something. “the project was subject to the usual vicissitudes of exploratory research” see more. noun. mutability in life or nature (especially successive alternation from one condition to another) see more. Cite this entry. Style: MLA.

  4. a change or variation occurring in the course of something. interchange or alternation, as of states or things. vicissitudes, successive, alternating, or changing phases or conditions, as of life or fortune; ups and downs: They remained friends through the vicissitudes of 40 years.

  5. VICISSITUDES definition: 1. changes that happen at different times during the life or development of someone or something…. Learn more.

  6. A usually unforeseen change in circumstance or experience that affects one's life, especially in a trying way: the vicissitudes of childhood. See Synonyms at difficulty. 2. The quality of being changeable; mutability: the vicissitude of fortune.

  7. one of the many changes and problems in a situation or in your life, that you have to deal with. Want to learn more? Definition of vicissitude noun in Oxford Advanced Learner's Dictionary. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more.

  8. 1. a. a condition of constant change or alternation, as a natural process; mutability. the vicissitude of the sea. b. regular succession or alternation, as of night and day. 2. [pl.] unpredictable changes or variations that keep occurring in life, fortune, etc.; shifting circumstances; ups and downs. 3.

  9. changes that happen at different times during the life or development of someone or something, especially those that result in conditions being worse: Losing your job is just one of the vicissitudes of life. SMART Vocabulary: related words and phrases.

  10. A condition of constant change or alternation, as a natural process; mutability. The vicissitude of the sea. Regular succession or alternation, as of night and day. Unpredictable changes or variations that keep occurring in life, fortune, etc.; shifting circumstances; ups and downs.

  11. Origin of vicissitude 1 First recorded in 1560–70; from Middle French, from Latin vicissitūdō, equivalent to viciss(im) “in turn” (perhaps by syncope, from unrecorded vice-cessim; vice “in the place of” + cessim “giving way,“ adverbial derivative of cēdere “to go, proceed”) + -i- -i- + -tūdō -tude ;see also vice 3

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