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      • The PCOH starting material can be purchased or prepared by reaction of phenyllithium or phenyl grignard with cyclohexanone. This alcohol is then be transformed into the amine by reaction with sodium azide (~90% yield) followed by reduction.
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  2. 1-Phenylcyclohexylamine | C12H17N | CID 31862 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

  3. Feb 6, 2010 · Molecular weight: 175.2701. IUPAC Standard InChI: InChI=1S/C12H17N/c1-3-7-11 (8-4-1)13-12-9-5-2-6-10-12/h1,3-4,7-8,12-13H,2,5-6,9-10H2. IUPAC Standard InChIKey: TXTHKGMZDDTZFD-UHFFFAOYSA-N. CAS Registry Number: 1821-36-9. Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file.

  4. Synthesis of PCP from PCA via 1-phenylcyclohexanol (PCOH) The PCOH starting material can be purchased or prepared by reaction of phenyllithium or phenyl grignard with cyclohexanone. This alcohol is then be transformed into the amine by reaction with sodium azide (~90% yield) followed by reduction.

  5. Apr 2, 2013 · Preparation and analytical characterization of 1‐ (1‐phenylcyclohexyl)piperidine (PCP) and 1‐ (1‐phenylcyclohexyl)pyrrolidine (PCPy) analogues - Wallach - 2014 - Drug Testing and Analysis - Wiley Online Library.

    • Jason Wallach, Giorgia De Paoli, Adeboye Adejare, Simon D. Brandt
    • 19
    • 2014
    • 02 April 2013
  6. Synthesis and anticonvulsant activity of 1-phenylcyclohexylamine analogues. | Semantic Scholar. DOI: 10.1021/JM00167A027. Corpus ID: 11849936. Synthesis and anticonvulsant activity of 1-phenylcyclohexylamine analogues. A. Thurkauf, B. de Costa, +4 authors. M. Rogawski. Published in Journal of Medicinal… 1 May 1990. Chemistry, Medicine. TLDR.

  7. Abstract. Thirty-eight analogues of 1-phenylcyclohexylamine (PCA), a phencyclidine (PCP) derivative, were examined for their activities in the mouse maximal electroshock (MES) seizure test and in a motor-toxicity assay. In addition, we determined the binding affinities of the compounds for PCP acceptor sites in rat brain membranes labeled with ...

  8. Sep 7, 2023 · Article. Synthesis and Analgesic Activity of New Analogs of 1- [1-phenylcyclohexyl]piperidine with Modified Structures in its Tricyclic System. Published: 07 September 2023. Volume 57 , pages 656–662, ( 2023 ) Cite this article. Download PDF. Pharmaceutical Chemistry Journal Aims and scope. Maryam Shokrollahi, Seyed Ali Sobhanian, Mohsen Khalili,

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