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      • Many fungi are able to induce their own exocytosis after they have been taken up by macrophages. The formation of hyphae by Candida albicans is induced within phagosomes and this activates a modified form of programmed cell death known as pyroptosis.
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  2. Apr 5, 2021 · The folding of fungal hyphae is promoted by Dectin-1, β2-integrin, VASP, actin–myosin polymerization, and cell motility. Folding facilitates the complete engulfment of long hyphae in some cases and it inhibits hyphal growth, presumably tipping the balance toward successful fungal clearance.

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      Innate immune cells such as macrophages recognize fungal...

  3. Nov 9, 2011 · Hyphae in mature biofilms show a strong propensity to invade the underlying substrate, even when there is little nutrient value (Figure 2(a)). In the mucosa, intercalation of hyphae disrupts the epithelial layer, which activates a localised inflammatory response.

    • Alexandra Brand
    • 10.1155/2012/517529
    • 2012
    • Int J Microbiol. 2012; 2012: 517529.
  4. Not only do fungi take up soluble soil phosphate more efficiently than unaided roots, they can also dissolve poorly-soluble phosphate esters present in acid soils, as well as dissolving phosphate from rock minerals (Chapter 5, p.181). Phosphate taken up by extraradical hyphae is accumulated as polyphosphate, in which form it is translocated in ...

  5. Feb 8, 2016 · Certain fungal species escape immune capture by generating cell types, such as Titan cells, elongated tubular hyphae or sporulating structures, known as spherules, that are too large to be...

    • Lars P. Erwig, Lars P. Erwig, Neil A. R. Gow
    • 2016
  6. Oct 1, 2018 · Several options are imaginable to allow a successful attack on hyphae: by molecules that (1) damage the integrity of the cell wall or the cytoplasmic membrane, (2) that enter hyphae and deploy their toxic activity in the cytoplasm, (3) that manipulate fungal signaling pathways and thereby harm the pathogen or (4) that deplete essential ...

    • Jürgen Löffler, Frank Ebel
    • 2017
  7. Sep 23, 2017 · Phagocytes are very efficient at recognizing fungi, mainly via interaction with the wall, which is composed of molecules that are not synthesized by the host and, therefore, are sensed as pathogen-associated molecular patterns (PAMPs) by different pattern recognition receptors (PRRs) [ 2 ].

  8. Jan 21, 2018 · Nutrient Absorption from a Host. Some hyphae of parasitic fungi are specialized for nutrient absorption within a specific host. These hyphae have specialized tips called haustoria, which penetrate the cell walls of plants or tissues of other organisms in order to obtain nutrients. Nutrient Absorption from Soil.

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