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Feb 20, 2024 · What initially was referred to as “Paxlovid rebound”—a return of COVID symptoms or test positivity after starting a course of the antiviral—is now more accurately referred to as “COVID rebound,” because rebound can happen regardless of whether someone takes antivirals. What’s more, it’s likely not a phenomenon unique to COVID ...
Mar 20, 2024 · COVID rebound occurs when someone who seems to have recovered from COVID-19 experiences a return of symptoms and a new positive test. Some studies have found the drug Paxlovid makes rebound more ...
May 13, 2022 · The news reports of Paxlovid rebound, though, have generated much interest. The initial trials using the drug looked highly successful in preventing hospitalization, with 87%-89% avoidance of 28 ...
Jul 21, 2022 · How effective is Paxlovid and what do we know about rebound infection? The FDA's initial authorization of Paxlovid was based on a trial run by Pfizer in at-risk unvaccinated adults.
May 6, 2022 · Rebound symptoms were lesser, and resolved after two days, but the patient had clear peaks in viral load on day 1 and day 9, and no other respiratory pathogens were detected, Michael Charness, MD ...
Jun 14, 2022 · It has been dubbed “Paxlovid Rebound.”. There is not much data on how frequently this occurs, but Pfizer’s application to the FDA for Emergency Use states that “several subjects appeared to have a rebound in SARS-CoV-2 RNA levels around Day 10 or Day 14.”. And according to Dr. Mikael Dolsten, Pfizer’s chief scientific officer, “We ...
Jun 14, 2022 · ROCHESTER, Minn. — Mayo Clinic researchers studied the outcomes of 483 high-risk patients treated for COVID-19 with a five-day oral regimen of nirmatrelvir and ritonavir, together marketed as Paxlovid. Only a handful developed COVID-19 rebound symptoms, and the researchers say more studies are needed to determine why. Overall, the treatment benefited everyone in the study. […]
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