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Apr 13, 2023 · PMCID: PMC10101523. DOI: 10.1371/journal.pone.0284292. Abstract. SLC35A3 is considered an uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) transporter in mammals and regulates the branching of N-glycans. A missense mutation in SLC35A3 causes complex vertebral malformation (CVM) in cattle.
Reviewer #2: The paper of Soichiro Saito and collaborators investigated the relationship between SLC35A3 and GAG synthesis by generating a KO SLC35A3 mice. They nicely showed that mice exhibited lethal chondrodysplasia with vertebral anomalies and impaired glycosaminoglycan biosynthesis.
- 10.1371/journal.pone.0284292
- 2023
- PLoS One. 2023; 18(4): e0284292.
Apr 13, 2023 · Open Access. Peer-reviewed. Research Article. Mice lacking nucleotide sugar transporter SLC35A3 exhibit lethal chondrodysplasia with vertebral anomalies and impaired glycosaminoglycan biosynthesis. Soichiro Saito , Shuji Mizumoto , Tsukasa Yonekura, Rina Yamashita, Kenta Nakano, Tadashi Okubo, Shuhei Yamada, Tadashi Okamura, Tatsuya Furuichi.
Feb 10, 2024 · Daihatsu President Soichiro Okudaira submits a report to transport minister Tetsuo Saito on measures the automaker will take to prevent a recurrence of safety testing fraud, on Friday in Tokyo....
- The Japan Times
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