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- Season 4 overviewNov 2, 2020-Jun 7, 202120 episodesSeason 4 episodes1. Frontline Part 1 Nov 2, 2020
- The team treats a patient who has an illness that is unlike anything it has seen before.
- 2. Frontline Part 2 Nov 9, 2020
- Dr. Shaun Murphy and the team try to get a better understanding of COVID-19.
- 3. Newbies Nov 16, 2020
- Lim tasks Shaun, Claire and Alex with mentoring the top first-year resident contenders.
- 4. Not the Same Nov 23, 2020
- The doctors are forced to grapple with a decision no one wants to make.
- 5. Fault Nov 30, 2020
- Dr. Murphy questions his decision to give the new residents autonomy.
- 6. Lim Jan 11, 2021
- Dr. Audrey Lim struggles to cope with the residual emotional trauma of COVID-19.
- 7. The Uncertainty Principle Jan 18, 2021
- Dr. Reznik discovers her patient's wealth and obsession with extending his life is a dangerous mix.
- 8. Parenting Jan 25, 2021
- The team treats a teenage gymnast who experiences complications from her intensive training.
- 9. Irresponsible Salad Bar Practices Feb 15, 2021
- Lim is challenged by the unique circumstances surrounding a pregnant patient with a tumor.
- 10. Decrypt Feb 22, 2021
- The hospital is hit with a cyberattack, threatening to shut down life-saving machines.
- 11. We're All Crazy Sometimes Mar 8, 2021
- Shaun and Morgan disagree on how to treat a comatose patient with a cancerous tumor.
- 12. Teeny Blue Eyes Mar 22, 2021
- Shaun and Lea are forced to make a decision that will alter the course of their relationship.
- 13. Spilled Milk Mar 29, 2021
- Shaun feels disconnected from Lea, causing tension in their relationship.
- 14. Gender Reveal Apr 19, 2021
- Lea's enthusiasm about her unborn child prompts Shaun to want to be a more supportive partner.
- 15. Waiting Apr 26, 2021
- After a political protest turns violent, the team races to save two young gunshot victims.
- 16. Dr. Ted May 10, 2021
- Dr. Park, Dr. Andrews and Asher disagree on how to address an elderly patient's wishes.
- 17. Letting Go May 17, 2021
- Dr. Claire Brown and the team must face hard truths about what lines they are willing to cross.
- 18. Forgive or Forget May 24, 2021
- Shaun and Lea go on a camping trip to distract themselves from their grief over their miscarriage.
- 19. Venga May 31, 2021
- The team travels to Guatemala on a mission to help patients at a rural hospital.
- 20. Vamos Jun 7, 2021
- Dr. Murphy must perform a risky surgery without electricity when the power suddenly goes out.