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  2. Release. October 15, 2007 (2007-10-15) – July 23, 2009 (2009-07-23) Samantha Who? is an American television sitcom that originally aired on ABC from October 15, 2007, to July 23, 2009. The series was created by Cecelia Ahern and Donald Todd, who also served as producers.

    • Sitcom
  3. Samantha Who? is a TV series that follows a woman who suffers from retrograde amnesia and tries to rebuild her life and relationships. The series features Christina Applegate, Jennifer Esposito, Melissa McCarthy and other stars, and won a Primetime Emmy.

    • (11K)
    • 2007-10-15
    • Comedy, Mystery, Romance
    • 22
  4. Samantha Who? is a comedy series starring Christina Applegate as a woman with amnesia who tries to be a better person. The show has mixed reviews from critics and audiences, and is available on Fandango at Home and Prime Video.

    • (28)
    • Christina Applegate
    • TV-PG
    • 2
  5. Watch the official Samantha Who? online at ABC.com. Get exclusive videos, blogs, photos, cast bios, free episodes

  6. Synopsis. Samantha Newly has been a bad, bad girl. But thanks to an 8-day coma, she can't remember a thing. Fortunately her best friend Andrea is by her side with a cocktail and the 4-1-1 on every dirty deed. But the more Sam pieces together her past, the less she likes her old self. Maybe this is a chance to start over and do it all again.

    • (165)
    • 2
    • TV-14
    • 7
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  8. Samantha Who? is a comedy-drama series about a woman who suffers from retrograde amnesia and tries to rediscover her life. The episode list shows the titles, ratings, and summaries of each episode of the two seasons of the show.

  9. May 24, 2024 · Samantha Who? is a TV show about a woman who wakes up from a coma and tries to change her life for the better. Watch full episodes online and learn more about the characters, cast and show information on the official ABC site.

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