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  2. Jan 6, 2022 · The Johnson & Johnson COVID-19 vaccine demonstrated a profile that showed durability of effectiveness up to 6 months for hospitalizations and ICU admissions across the study period, with a modest increase in breakthrough infections starting in month 4.

  3. Mar 19, 2022 · Coronavirus. As picture of Covid vaccine durability gets clearer, J&J makes a strong showing. This week, Pfizer and Moderna asked the FDA to authorize fourth doses of their vaccines. Meanwhile, a...

  4. Jul 2, 2021 · The Johnson & Johnson coronavirus vaccine provides immunity that lasts at least eight months, and it appears to provide adequate protection against the worrying Delta variant, the company...

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    • What Is in The Vaccine and How Does It Work?
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    Vaccine name:Ad26.COV2.S Design type:Adenovirus viral vector Dose number:1 dose, with a “booster” dose recommended for all adults at least two months later. At least two months after getting either 1 or 2 doses of the J&J vaccine, adults should get 1 bivalent mRNA shot, the CDC recommends. Efficacy:Overall, 66.1% efficacyin preventing moderate to s...

    The design is different from the mRNA vaccines authorized in December, but all of the vaccines fundamentally work in the same way: They trigger an immune responseagainst the SARS-CoV-2 virus’s spike protein, which sits on the surface of the virus and is what the virus uses to enter cells. The Johnson & Johnson vaccine uses another, harmless virus —...

    Johnson & Johnson has experience working with adenovirus-based vaccines, and gained approvalin Europe in July for an Ebola vaccine that uses this technology. The company is also workingon adenovirus-based vaccines for HIV and Zika. In January 2020, when the sequence for SARS-CoV-2 became available, Johnson & Johnson collaborated with Harvard’s Beth...

    In its primary clinical trial, which was conducted in 2020 before the advent of the delta or omicron variants, J&J reported66.1% efficacy globally in preventing moderate to severe COVID-19 in adults 28 days or more after vaccination, and an efficacy of 85.4% in preventing severe or critical COVID-19. The efficacy was similar across demographics inc...

    There were “no specific safety concerns” identified in the trial, the FDA briefing document said. Some of those receiving the vaccine did report side effects, including injection site pain, headache, fatigue and myalgia (muscle pain or ache), generally lasting a day or two post-vaccination. These side effects were more common in 18- to 59-year-old ...

  5. Mar 5, 2021 · How long does it take for protection to kick in? With all three vaccines, immunity builds over a few weeks after immunization.

  6. Sep 21, 2021 · Booster shot at two months provided 94 percent protection against COVID-19 in the U.S. The Phase 3 ENSEMBLE 2 study showed that another shot of the Johnson & Johnson COVID-19 vaccine given 56 days after the first provided: 100 percent protection (CI, 33%-100%) against severe/critical COVID-19 – at least 14 days post-final vaccination.

  7. Aug 18, 2021 · Editor’s note: On Oct. 20, the Food and Drug Administration gave Emergency Use Authorization to a second shot of the Johnson and Johnson COVID-19 vaccine at least two months after the first dose.

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