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Apr 14, 2011 · Otto Warburg pioneered quantitative investigations of cancer cell metabolism, as well as photosynthesis and respiration. Warburg and co-workers showed in the 1920s that, under aerobic...
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May 12, 2016 · In the early 20th century, the German biochemist Otto Warburg believed that tumors could be treated by disrupting their source of energy. His idea was dismissed for decades — until now.
In the 1920s, Dr. Otto Warburg, a German researcher, found that cancer cells prefer the anaerobic, or oxygen-free, process of fermentation for generating energy.
May 21, 2021 · While his contemporaries hypothesized that tumor cells derived the energy required for uncontrolled replication from proteolysis and lipolysis, Warburg instead found them to rapidly consume glucose, converting it to lactate even in the presence of oxygen.
- Sminu Bose, Cissy Zhang, Anne Le
- 2021/05/21
- 10.1007/978-3-030-65768-0_1
Apr 15, 2024 · Otto Warburg (born October 8, 1883, Freiburg im Breisgau, Germany—died August 1, 1970, West Berlin, West Germany) was a German biochemist awarded the Nobel Prize for Physiology or Medicine in 1931 for his research on cellular respiration.
- The Editors of Encyclopaedia Britannica
Aug 4, 2020 · The Warburg effect is generally thought to confer growth advantages to tumor cells including the rapid supply of ATP, amino acids for protein synthesis, nucleic acids for DNA duplication, and lipids for cell biomembrane synthesis, which may be needed in cell proliferation.
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Nov 21, 2023 · Two of the most fundamental discoveries of the 1920s were the demonstration that tumour samples exhibited aerobic glycolysis rather than oxidative respiration, by Otto Warburg, and the...
