Search results
- Population Differentiation Among European Populations
- Principal Components Analyses Using >250,000 SNPs
- PCA of Northern and Southern European Population Groups
- PCA of European and South Asian Population Groups
- Identification and Testing of European Substructure Ancestry Informative Markers
- Performance of Esaims in Controlling For Population Substructure
To examine similarities and differences in population differentiation among European and closely related populations, paired Fst values were determined between 18 population groups that were typed with genome-wide SNP arrays (see Materials and Methods). The studies included genotypes derived from HGDP (14), and samples collected in Europe and Europ...
To further explore the relationship among European population groups and examine population substructure, PCA was performed using the genotype results from a set of ~300,000 autosomal SNPs that was common to each of the populations examined. For most individuals with self-reported ethnic identities there was a general correspondence with the geogra...
Our previous studies showed that further elucidation of the relationships among Northern European individuals was possible when analyses were performed excluding subjects of southern European origin. For the current study, we next examined Northern and Southern population groups separately and the effect of including or excluding different ethnic g...
To further explore the relationship of population groups in Europe, we also performed PCA including the HGDP South Asian groups, Burusho, and Balochi. These South Asian population groups showed relatively small population differentiation with continental European subjects (14,17,26,27). Thus inclusion of these populations might further suggest clin...
AIMs that discern population substructure are likely to be useful in candidate gene, chromosomal position-based association studies, and defining homogeneous subject sets (28). Our previous studies identified two sets of European substructure AIMs (ESAIMs): ns-ESAIMs and north-ESAIMs. The ns-ESAIMs separated European populations on a single axis (n...
To further assess the potential value and performance of ESAIMs we examined SNPs with large (10% to 25%) allele frequency differences between different European subgroups. The different subgroups were selected based on PCA results and included both individuals with self-identified ethnic affiliation and those without known self-identity information...
- Chao Tian, Roman Kosoy, Rami Nassir, Annette Lee, Pablo Villoslada, Lars Klareskog, Lennart Hammarst...
- 2009
Feb 9, 2024 · The 2023 update of the European Definition of General Practice/Family Medicine keeps the six core competencies, twelve characteristics and three additional features of GP/FM in the European Definition of GP/FM as they already encompass the concepts of planetary health, one health and sustainability.
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Do European population substructures correspond to geographic relationships?
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Aug 24, 2009 · The definition of European population genetic substructure and its application to understanding complex phenotypes is becoming increasingly important. In the current study using over 4000 subjects genotyped for 300 thousand SNPs we provide further insight into relationships among European population groups and identify sets of SNP ancestry ...
The revised European Definition of General Practice/Family Medicine. A pivotal role of One Health, Planetary Health and Sustainable Development Goals. Eur J Gen Pract. 2024 Dec;30 (1):2306936. doi: 10.1080/13814788.2024.2306936. Epub 2024 Feb 9. Authors. A Windak 1 2 3 , A Rochfort 4 5 6 , J Jacquet 7 8. Affiliations.
European population genetic substructure: further definition of ancestry informative markers for distinguishing among diverse European ethnic groups. Mol Med. 2009 Nov-Dec;15 (11-12):371-83. doi: 10.2119/molmed.2009.00094. Epub 2009 Aug 27.
Clinical decisions take into consideration of ambulatory clinical context, patient’s preferences in its living environment and current scientific data, in an EBM model. This definition is worth to be implemented in the three components of a medical discipline: care, teaching and research.
2 days ago · Serum lactate is associated with mortality in diverse kinds of patients. This study aimed to investigate whether serum lactate level may independently predict mortality in acute kidney injury (AKI) patients. Meng Chen and Dezhao Lv. European Journal of Medical Research 2024 29 :295. Research Published on: 22 May 2024.
