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Introduced in 1935 by Gerhard Domagk (1895–1964), sulfa drugs, or sulfonamides, all of which are related to the compound sulfanilamide, provided the first successful therapies for many bacterial diseases.
Apr 20, 2024 · Gerhard Domagk was a German bacteriologist and pathologist who was awarded the 1939 Nobel Prize for Physiology or Medicine for his discovery (announced in 1932) of the antibacterial effects of Prontosil, the first of the sulfonamide drugs.
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Bacteriology. Gerhard Johannes Paul Domagk ( German pronunciation: [ˈɡeːɐ̯haʁt ˈdoːmak] ⓘ; 30 October 1895 – 24 April 1964) was a German pathologist and bacteriologist . He is credited with the discovery of sulfonamidochrysoidine (KL730) as an antibiotic for which he received the 1939 Nobel Prize in Physiology or Medicine.
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Dec 25, 2022 · GERHARD DOMAGK (1895-1964) written by DrChika December 25, 2022. Gerhard Domagk was a German pathologist and bacteriologist who reported in 1935 that prontosil (a red dye used for staining leather) was active against pathogenic Staphylococci and Streptococci in mice.
Dec 8, 2010 · During the earlier days of antibiotics research, this approach led to the discovery of sulfa drugs, namely sulfonamidochrysoidine (KI-730, Prontosil), which was synthesized by Bayer chemists Josef Klarer and Fritz Mietzsch and tested by Gerhard Domagk for antibacterial activity in a number of diseases (Domagk, 1935). Prontosil, however ...
- Rustam I. Aminov
- 2010
This led to the search for chemical preparations to combat bacteria and other microorganisms. The challenge was long thought to be impossible, but in 1932 Gerhard Domagk and his colleagues demonstrated in mice experiments that sulfonamides could be used to counteract bacteria that cause blood poisoning.
Oct 1, 2019 · Current Opinion in Microbiology. Antibiotics: past, present and future. The first antibiotic, salvarsan, was deployed in 1910. In just over 100 years antibiotics have drastically changed modern medicine and extended the average human lifespan by 23 years. The discovery of penicillin in 1928 started the golden age of natural product antibiotic ...
