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  2. Apr 9, 2020 · Thursday, April 09, 2020 - 07:50am. View pdf copy Copy to clipboard Open in tab. Pfizer and BioNTech to jointly develop COVID-19 vaccine, initially in the United States and Europe, and scale-up manufacturing capacity to support global supply. Potential to supply millions of vaccine doses by the end of 2020 subject to technical success of the ...

  3. The Pfizer-BioNTech COVID19 Vaccine is authorized for use under an Emergency Use Authorization (EUA) for active immunization to prevent coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARSCoV2) in individuals 16 years of age and older.

    • What Is in The Vaccine and How Does It Work?
    • How Was The Vaccine developed?
    • How Effective Is The Vaccine?
    • How Safe Is The Vaccine?
    • Why Does The Vaccine Need to Be Kept So Cold?

    As with most other COVID-19 vaccine designs, the Pfizer/BioNTech mRNA vaccine works by triggering an immune responseagainst the spike protein of the SARS-CoV-2 virus, which sits on the surface of the virus and is what the virus uses to enter cells. The vaccine is made of modified messenger RNA, or mRNA, wrapped in a special blend of fatty molecules...

    German company BioNTech designed multiple mRNA vaccine candidates after the genetic sequence of the SARS-CoV-2 virus became public in January 2020 and partneredwith Pfizer in March 2020. Early phase clinical trialsshowed that two leading mRNA designs triggered neutralizing antibody responses that were better than those from people recovering from n...

    In the updatedtrial resultsreported to the FDA for full approval, the Pfizer/BioNTech vaccine was 91% effective in preventing symptomatic disease at least a week after the second dose in people 16 years of age and older. This does notmeanthat the vaccine works 91% of the time or that 9% of vaccinated people will fall ill with COVID-19. Instead, as ...

    In clinical trials and in subsequent safety monitoring, the Pfizer/BioNTech vaccine has been shown to be very safe. While many people experience unpleasant side effects,the vaccine only very rarely appears to cause more serious problems. This includesserious allergic reactions, such as anaphylaxis, and an increased risk of inflammation of the heart...

    The extreme cold is necessaryto keep the highly sensitive lipid-encapsulated RNA molecules from degrading. Logistically, this cold chain requirement poses an extra hurdle in distributing the vaccine, since many potential vaccination sites lack the appropriate ultracold freezers and may not have a ready source of dry ice. Pfizer has tried to mitigat...

  4. Aug 23, 2021 · August 23, 2021. Español. Today, the U.S. Food and Drug Administration approved the first COVID-19 vaccine. The vaccine has been known as the Pfizer-BioNTech COVID-19 Vaccine, and will now be...

  5. Syringes containing Pfizer COVID-19 vaccine doses. BioNTech announced in September 2020, that it had signed an agreement to acquire a manufacturing facility in Marburg, Germany, from Novartis to expand their vaccine production capacity.

  6. Jun 29, 2022 · June 29, 2022 04:45 PM Eastern Daylight Time. NEW YORK & MAINZ, Germany-- ( BUSINESS WIRE )--Pfizer Inc. (NYSE: PFE) and BioNTech SE (Nasdaq: BNTX) today announced a new vaccine supply...

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