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  1. Saint Charles (commonly abbreviated St. Charles) is a city in, and the county seat of, St. Charles County, Missouri, United States. [2] The population was 70,493 at the 2020 census, making St. Charles the 9th most populous city in Missouri. Situated on the Missouri River, St. Charles is a northwestern suburb of St. Louis .

  2. Saint Charles is a city in, and the county seat of, St. Charles County, Missouri, United States. The population was 70,493 at the 2020 census, making St. Charles the 9th most populous city in Missouri. Situated on the Missouri River, St. Charles is a northwestern suburb of St. Louis.

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  4. Step back in time to a historical place with a slower pace. With a unique blend of 19th-century architecture, intriguing historic sites, and one-of-a-kind shops and restaurants, Historic St. Charles, Missouri, is a place where the essence of history and life in a simpler time envelops you.

  5. About The Area. History. St. Charles History. Founded in 1769 as Les Petites Cotes ("The Little Hills") by French Canadian fur trader Louis Blanchette. The Spanish government controlled the Mississippi Valley between 1762-1800, and for a dozen years "The Little Hills" became "San Carlos Borromeo."

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