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  2. Apr 19, 2023 · 1994: The first GMO produce created through genetic engineering—a GMO tomato—becomes available for sale after studies evaluated by federal agencies proved it to be as safe as traditionally...

  3. This breakthrough in genetic engineering soon allowed for the development of bacteria to produce human insulin for diabetic patients, which in 1982 became the first consumer GMO product approved by the U.S. Food and Drug Administration (FDA).

    • Melissa Petruzzello
    • Escherichia coli. In November 1973, geneticist Stanley Cohen and colleagues reported that they had built a plasmid, a ring of DNA, that carried a gene from another organism into an E. coli cell — the birth of genetic engineering (SN: 6/1/74).
    • Transgenic mice. Mouse models are a go-to for scientists who want to study human disease in a controlled way in the lab. In 1974, biologists Rudolf Jaenisch and Beatrice Mintz laid the groundwork for these models by injecting DNA from simian virus into mouse embryos, which were later born with viral DNA in their genomes.
    • Bt tobacco and more. In 1987, geneticist Mark Vaeck and colleagues reported that they had genetically engineered tobacco to produce Bt toxins. These toxins, made by the bacterium Bacillus thuringiensis, affect only certain insects, including several common agricultural pests.
    • Flavr Savr tomato. The impact of the Flavr Savr tomato, introduced in 1994, is largely symbolic (SN: 5/28/94). Its genome was modified to block the production of an enzyme responsible for fruit softening, thus keeping the fruit firm longer.
    • Ancient Genetic Modification
    • The Birth of Modern Genetic Modification
    • Use of Genetically Engineered Organisms
    • Genetically Engineered Food Controversies
    • The Future of GMO Technology

    While our ancestors had no concept of genetics, they were still able to influence the DNA of other organisms by a process called “selective breeding” or “artificial selection.” These terms, coined by Charles Darwin, describe the process of choosing the organisms with the most desired traits and mating them with the intention of combining and propag...

    An enormous breakthrough in GMO technology came in 1973, when Herbert Boyer and Stanley Cohen worked together to engineer the first successful genetically engineered (GE) organism . The two scientists developed a method to very specifically cut out a gene from one organism and paste it into another. Using this method, they transferred a gene that e...

    In 1980, the U.S. Supreme Court of the ruled that scientists from General Electric could patent bacteria that were genetically engineered to break down crude oil to help with oil spill mitigation . This ruling legally permitted ownership rights over GMOs, giving large companies the incentive to rapidly develop GMO tools that could both be useful an...

    There have been many controversies regarding GE technology, with the majority relating to GE food. While some critics object to the use of this technology based on religious or philosophical bases, most critics object on the basis of environmental or health concerns. For instance, a 1999 publication showed Bt toxin had negative effects on butterfly...

    There are countless potential uses of GE technology in development. These include plants with superior disease and drought resistance, animals with enhanced growth properties, and strategies for more efficient pharmaceutical production . Likewise, GE technology itself is quickly advancing. Recently, researchers have developed a new technology calle...

  4. The first genetically modified food approved for release was the Flavr Savr tomato in 1994. Developed by Calgene, it was engineered to have a longer shelf life by inserting an antisense gene that delayed ripening. China was the first country to commercialize a transgenic crop in 1993 with the introduction of virus-resistant tobacco.

  5. Mar 10, 2013 · 1982 - FDA Approves First GMO. Humulin, insulin produced by genetically engineered E. coli bacteria, appears on the market. 1994 - GMO Hits Grocery Stores. The U.S. Food and Drug Administration approves the Flavr Savr tomato for sale on grocery store shelves.

  6. Jul 23, 2018 · From peas to trees. Scientists wielding high tech tools like garden trowels, watering cans, and fountain pens launched the genetic engineering age, long before the advent of GMOs and bioengineered food. I wonder what early genetic engineers would think about today’s biotech industry.

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