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    • Emmy Rossum (Fiona Gallagher) As Fiona Gallagher, the oldest sibling who took on most of the responsibilities in the multi-child house, Emmy Rossum played her most well-known role to date in Shameless, and it was certainly the one she played the longest too.
    • Joan Cusack (Sheila Jackson) In her Emmy-winning role as Sheila Jackson, Joan Cusack played a memorable part in Shameless as the kind and caring (if somewhat absent-minded) mother of Karen.
    • Justin Chatwin (Steve Wilton/Jimmy Lishman/Jack) Playing Jimmy Lishman, who also went by the names Steve Wilton and "Jack," Justin Chatwin played a prominent part in Shameless Seasons 1-3.
    • Laura Slade Wiggins (Karen Jackson) Throughout the first two seasons of Shameless, Laura Slade Wiggins played the recurring role of Karen Jackson, Lip's friend-with-benefits who found herself suffering frontal-lobe brain damage during the end of her time on the show.
  1. May 17, 2012 · Laura Slade Wiggins is notorious for playing Karen on Showtime’s ‘Shameless’. Unlike Karen, who may be one of the most hated characters currently on ‘ Shameless ‘, Laura is a complete sweetheart!

  2. Her attempt to win Lip back culminates in tragedy when Mandy strikes Karen with her car out of jealousy, leaving her with permanent brain damage. This incident leads Karen to leave Chicago and...

  3. Feb 2, 2023 · Karen was played by the insanely talented Laura Slade Wiggins, and while Wiggins was only a part of the Shameless cast for two seasons, her performance made a lasting impression.

    • Why did Laura Slade Wiggins leave 'nerdy with US'?1
    • Why did Laura Slade Wiggins leave 'nerdy with US'?2
    • Why did Laura Slade Wiggins leave 'nerdy with US'?3
    • Why did Laura Slade Wiggins leave 'nerdy with US'?4
    • Why did Laura Slade Wiggins leave 'nerdy with US'?5
  4. Feb 7, 2023 · With that in mind, it seems likely that Wiggins was sad to leave the beloved show behind so early on but it felt like there wasn't much left to do with her character. Whether Wiggins was happy or sad to leave Shameless, life has continued for the talented actor.

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  5. Apr 6, 2013 · Fans of Laura Slade Wiggins were ecstatic to see Laura reprise her role of Karen for Showtime’s hit series ‘Shameless’. The season three finale airs tomorrow night a 9PM ET/PT. You don’t want to miss it! Read our interview with Laura below. We discuss Karen’s future, Sleeping Beauty, and Mandy Milkovich.

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  7. Apr 25, 2014 · Parade sat down with the film’s star Laura Slade Wiggins to discuss Starving in Suburbia, her own personal battles with eating disorders, and if she’ll ever return to Shameless. How did you...

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