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  1. Biographical summary. Erin O'Brien, M.D., is a fellowship trained rhinologist with a specialty interest in chronic rhinosinusitis, nasal polyps, aspirin exacerbated respiratory disease (AERD: nasal polyps, asthma, aspirin sensitivity), benign sinus tumors, cerebrospinal fluid (CSF) leaks in the nose, and skull base surgery.

    • Rochester, MN
    • Focus Areas
    • Significance to Patient Care
    • Professional Highlights
    AERD— Using mass cytometry of sinus tissue and polyps, biomarker discovery for inflammatory cells, and markers for diagnosis and disease response to therapy and exacerbations
    Acute and chronic rhinosinusitis diagnosis— Researching cytology and microbial markers for diagnosis of sinusitis beyond culture results
    Chronic rhinosinusitis in systemic diseases— Examining symptoms and presentation of chronic rhinosinusitis in systemic diseases such as vasculitis, inflammatory bowel disease, immunoglobulin G4 (Ig...

    Dr. O'Brien's research on chronic rhinosinusitis and associated diseases, such as asthma, aligns with her clinical collaborations with Mayo Clinic colleagues in allergy, pulmonary medicine, rheumatology and other specialties. She hopes that her research to identify biomarkers and to subtype different causes for sinusitis will allow for more targete...

    Membership chair, American Rhinologic Society, 2018-2021
    Member, Diversity and Inclusion Committee, American Rhinologic Society, 2020-present
    Founding member, Women in Rhinology Section, American Rhinologic Society, 2018-present
    Head and neck surgery oral board examiner, American Board of Otolaryngology — Head and Neck Surgery, 2017-present
  2. EK O’Brien, X Zhang, C Nishimura, JB Tomblin, JC Murray. The American Journal of Human Genetics 72 (6), 1536-1543. , 2003. 178. 2003. Elevated body mass index and risk of postoperative CSF leak following transsphenoidal surgery. BJ Dlouhy, K Madhavan, JD Clinger, A Reddy, JD Dawson, EK O'Brien, ...

  3. Erin K. O'Brien, M.D. Otolaryngologist. Request an Appointment. Overview. Publications. Falde SD, Fussner LA, Tazelaar HD, O'Brien EK, Lamprecht P, Konig MF, Specks U. Proteinase 3-specific antineutrophil cytoplasmic antibody-associated vasculitis. Lancet Rheumatol. 2024 May; 6 (5):e314-e327 Epub 2024 Apr 01. View PubMed.

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  5. ERIN K. O’BRIEN, M.D. Dr. O’Brien is an associate professor in the department of Otolaryngology-Head and Neck Surgery at Mayo Clinic Rochester. She is the department’s first diversity leader and current chair of the division of rhinology.

  6. Erin K. O'Brien, MD. Rhinology. Mayo Clinic200 1st St SW ENT Gonda 12Rochester MN 55905-0002 United States(507) 284-1482. Visit Website. About. Hospital Affiliation. Mayo Clinic. Education. Fellowship: Rhinology. Residency: University of Iowa Hospital and Clinics - 2007. Medical School: University of Pittsburgh School of Medicine - 2000.

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