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Opioids are a class of drugs that derive from, or mimic, natural substances found in the opium poppy plant. Opioids work in the brain to produce a variety of effects, including pain relief. As a class of substances, they act on opioid receptors to produce morphine-like effects. The terms 'opioid' and 'opiate' are sometimes used interchangeably, but there are key differences based on the manufactur... Wikipedia