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Learn how giant cell arteritis is diagnosed and treated with corticosteroids, immune-suppressing drugs or tocilizumab. Find out about possible side effects, lifestyle tips and clinical trials.
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Jan 17, 2024 · Learn about the initial management of giant cell arteritis (GCA), a systemic vasculitis that affects older adults. Find out how to use high-dose glucocorticoids, glucocorticoid-sparing agents, and glucocorticoid tapering to prevent visual loss and complications.
Giant cell arteritis (GCA) is a type of vasculitis that affects older adults and can cause vision loss, headache, fever, and joint pain. Learn how GCA is diagnosed by biopsy and blood tests, and how it is treated with prednisone and other medications.
- GCA is a disease of older people. The average age at onset is 72, and almost all people with the disease are over the age of 50. Women are afflicte...
- The most common symptoms of GCA are headache, pain in the shoulders and hips (called polymyalgia rheumatica), pain in the jaw after chewing (called...
- We do not know. We do know that aging has something to do with the disease. And we know that the body’s immune system attacks and inflames the arte...
- The diagnosis is made by doing a biopsy of the temporal artery. Using a local numbing medication (the same one used by a dentist), the doctor can r...
- GCA requires treatment with prednisone, a type of corticosteroid. Typically, treatment begins with 40–60 mg of prednisone, taken by mouth each day....
- A discussion of Giant Cell Arteritis written in medical terms by David Hellmann, M.D. (F.A.C.P.), Co-Director of the Johns Hopkins Vasculitis Cente...
Learn about the symptoms, causes, diagnosis and treatment of temporal arteritis, a form of vasculitis that affects the arteries of your scalp, neck and arms. Find out how corticosteroids can help prevent vision loss and other complications.
Giant cell arteritis (GCA) is the most common primary systemic vasculitis in adults 50 years or older. Expanded use of advanced arterial imaging has assisted both in the diagnosis of GCA and recognition of disease subsets. Although glucocorticoids have been the mainstay of treatment for almost 7 decades, new therapeutic options have emerged.
- Thomas D. Garvey, Matthew J. Koster, Kenneth J. Warrington
- 2021
Giant cell arteritis frequently causes headaches, scalp tenderness, jaw pain and vision problems. Untreated, it can lead to blindness. Prompt treatment with corticosteroid medications usually relieves symptoms of giant cell arteritis and might prevent loss of vision.
Mar 13, 2022 · Among them, the more promising targets in GCA treatment are the IL12/IL23 axis antagonists, IL17 inhibitors, modulators of T lymphocytes, and inhibitors of either the JAK/STAT pathway, the granulocyte-macrophage colony-stimulating factor, or the endothelin, all of which are updated in this review.
