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1. www.rarediseaseadvisor.com › hcp-resource › ancaANCA-Associated Vasculitis Life Expectancy - Rare Disease Advisor

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   Because ANCA specificity has been shown to be predictive of relapse, a patient’s AAV type can affect their life expectancy. Patients with autoantibodies against PR3 are more than twice as likely to relapse as those who have autoantibodies against the MPO protein.

2. academic.oup.com › rheumatology › articleLong-term outcomes in elderly patients with ANCA-associated ...

   academic.oup.com › rheumatology › article

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   Sep 17, 2019 · During follow-up, 21 patients (25%) died; median time to death was 453 days (IQR 176–1090). Two-year and five-year survival in the whole cohort were 83% (95% CI 75, 92%) and 75% (95% CI 65, 86%), respectively (Fig. 1). Remission was achieved in 70 patients after a median of 125 days (IQR 92–179).

   • Author: Dominic McGovern, Sam P Williams, Katrina Parsons, Tariq E Farrah, Peter J Gallacher, Eve Miller-Hod...

   • Publish Year: 2020

3. www.rarediseaseadvisor.com › disease-info-pagesANCA-Associated Vasculitis Prognosis - Rare Disease Advisor

   www.rarediseaseadvisor.com › disease-info-pages

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   Read more about AAV life expectancy. Effects of Treatment on Prognosis of GPA. The prognosis for patients with GPA has improved with the use of immunosuppressive therapy, but the overall survival and risk of relapse vary depending on the severity and extent of organ involvement.

4. www.ncbi.nlm.nih.gov › pmc › articlesOutcome and Treatment of Elderly Patients with ANCA ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Jul 7, 2015 · Overall 1-year survival was 71.5% and 2-year survival was 64.6%. Older age, higher creatinine, and lower Birmingham Vasculitis Activity Score were associated with higher mortality in multivariable analysis. Patients who were not treated with standard immunosuppressive therapy had significantly worse survival. Renal survival was 74.8% at 1 year.

   • Author: Maria Weiner, Su Mein Goh, Aladdin J. Mohammad, Zdenka Hruskova, Anisha Tanna, Annette Bruchfeld, Da...
   • DOI: 10.2215/CJN.00480115

   • Publish Year: 2015
   • Published: 2015/07/07

5. www.mayoclinic.org › medical-professionalsUpdate on the management of ANCA-associated vasculitis

   www.mayoclinic.org › medical-professionals

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   Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis comprises three syndromes, all with frequent respiratory manifestations. Studies indicate that ANCA specificity is more important for prognosis, relapse risk, response to therapy and outcomes than the specific diagnosis.

6. pubmed.ncbi.nlm.nih.gov › 21109517Long-term patient survival in ANCA-associated vasculitis

   pubmed.ncbi.nlm.nih.gov › 21109517

   Patients with ANCA-associated vasculitis treated with conventional regimens are at increased risk of death compared with an age- and sex-matched population.

7. People also ask

   Does ANCA specificity affect life expectancy?

   • Because ANCA specificity has been shown to be predictive of relapse, a patient’s AAV type can affect their life expectancy. Patients with autoantibodies against PR3 are more than twice as likely to relapse as those who have autoantibodies against the MPO protein.

   ANCA-Associated Vasculitis Life Expectancy - Rare Disease Advisor

   www.rarediseaseadvisor.com/hcp-resource/anca-associated-vasculitis-life-expectancy/

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   Does age affect mortality in elderly patients with ANCA vasculitis?

   • Age, frailty score and CRP are associated with mortality in elderly patients with ANCA vasculitis. Patients aged >75, or with a Rockwood Clinical Frailty score of ⩾4, have higher mortality. ANCA-associated vasculitis (AAV) is a small-vessel vasculitis that may present at any age. The incidence peaks in the seventh and eighth decades [1–3].

   Long-term outcomes in elderly patients with ANCA-associated vasculitis

   academic.oup.com/rheumatology/article/59/5/1076/5570881

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   What is the prognosis of ANCA-associated vasculitis?

   • ANCA-associated vasculitis is a disease with substantial mortality and morbidity among elderly patients. This study showed a better prognosis for those who received immunosuppressive treatment and those who were diagnosed before having developed advanced renal insufficiency. Keywords: ANCA, GN, survival, vasculitis

   Outcome and Treatment of Elderly Patients with ANCA-Associated

   www.ncbi.nlm.nih.gov/pmc/articles/PMC4491279/

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   Is glucocorticoid-sparing a good treatment for ANCA vasculitis in the elderly?

   • A glucocorticoid-sparing regimen can give good long-term clinical outcomes in ANCA vasculitis in the elderly. Age, frailty score and CRP are associated with mortality in elderly patients with ANCA vasculitis. Patients aged >75, or with a Rockwood Clinical Frailty score of ⩾4, have higher mortality.

   Long-term outcomes in elderly patients with ANCA-associated vasculitis

   academic.oup.com/rheumatology/article/59/5/1076/5570881

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8. bmcnephrol.biomedcentral.com › articles › 10Early predictors of one-year mortality in patients over 65 ...

   bmcnephrol.biomedcentral.com › articles › 10

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   Nov 9, 2018 · When considering various disease severity markers in over-65 patients with ANCA-associated renal vasculitis, we found that an early, severe infection (which occurred in about a quarter of the patients) is a strong predictor of one-year mortality.