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    • Image courtesy of researchgate.net

      researchgate.net

      • Focal lesions are early, abnormal areas in the bone marrow that signal the development of a lytic lesion within the next 18-24 months. An otherwise asymptomatic patient whose MRI scan shows more than 1 focal lesion of at least 5 mm in size has what is called a "myeloma-defining event," and should be treated for active disease.
      www.myeloma.org › bone-disease
  1. Jul 18, 2023 · Infections, fractures, and tumors can cause a bone lesion. Treatment can depend on the cause, but might include medication and surgery. When cells within the bone start to divide...

    • Amanda Barrell
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  3. Focal lesions in bone are very common and many of these lesions are not bone tumors. These bone tumor mimickers can include numerous normal anatomic variants and non-neoplastic processes. Many of these tumor mimickers can be left alone, while others can be due to a significant disease process.

    • Jennifer Ni Mhuircheartaigh, Yu-Ching Lin, Jim S Wu
    • 10.4103/0971-3026.137026
    • 2014
    • Jul-Sep 2014
  4. Aug 16, 2023 · Doctors use the term “focal lesions” to refer to an abnormal area of bone marrow that will develop into a lytic lesion within 18–24 months. What do they look like? How does MM cause bone ...

  5. May 11, 2024 · The cause of most bone cancers isn't known. Bone cancer starts when cells in or near a bone develop changes in their DNA. A cell's DNA holds the instructions that tell the cell what to do. In healthy cells, the DNA gives instructions to grow and multiply at a set rate.

  6. Apr 27, 2022 · Overview. Symptoms. When to see a doctor. Causes. Risk factors. Overview. Bone metastasis occurs when cancer cells spread from their original site to a bone. Nearly all types of cancer can spread (metastasize) to the bones. But some types of cancer are particularly likely to spread to bone, including breast cancer and prostate cancer.

  7. Sep 13, 2022 · Osteolytic lesions, also called osteoclastic or lytic lesions, are areas of damaged bone that most often occur in people with certain cancers, such as multiple myeloma and breast cancer. On an X-ray, osteolytic lesions appear as tiny holes, giving the bone a "moth-eaten" or "punched-out" appearance.

  8. Oct 2, 2020 · Benign lesions form in a bone and can grow locally but do not spread to other organs to cause harm. Malignant lesions, more commonly referred to as cancer, are lesions which may form and develop in the bone but have the capacity to spread to other areas of the body and continue to grow.

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