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    • Image courtesy of frontiersin.org

      frontiersin.org

      • Symptoms of the lower respiratory tract secondary to lung nodules and alveolar hemorrhage sometimes can be severe and fatal. Rarely it can cause tracheal stenosis. Renal involvement can cause rapidly progressive renal failure.
      www.ncbi.nlm.nih.gov › books › NBK554372
  1. Jul 5, 2019 · For major relapses, including severely damaging, potentially organ-threatening or life-threatening ANCA-associated vasculitis, rituximab or cyclophosphamide with glucocorticoids is recommended.

    • Mark McClure, Rachel B. Jones
    • 2019
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  3. Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis comprises three syndromes, all with frequent respiratory manifestations. Studies indicate that ANCA specificity is more important for prognosis, relapse risk, response to therapy and outcomes than the specific diagnosis.

  4. Nov 28, 2020 · Clinical relapses are common in patients with ANCA-associated vasculitis (AAV). The aim of this systematic review was to estimate time-point prevalence and risk factors of relapse. Methods. We searched PubMed, Embase, and Cochrane Library databases from their inception to March 30, 2020.

    • Peng He, Jin-Ping Hu, Xiu-Juan Tian, Li-Jie He, Shi-Ren Sun, Chen Huang
    • 2021
  5. Apr 8, 2021 · The first Maintenance of Remission using Rituximab in Systemic ANCA-Associated Vasculitis (MAINRITSAN) study included newly diagnosed, severe relapsing GPA or MPA, or renal-limited ANCA-associated vasculitis.

    • Karla N. Samman, Carolyn Ross, Christian Pagnoux, Jean-Paul Makhzoum
    • 10.1155/2021/5534851
    • 2021
    • Int J Rheumatol. 2021; 2021: 5534851.
  6. Mar 2, 2021 · Background: Clinical relapses are common in patients with ANCA-associated vasculitis (AAV). The aim of this systematic review was to estimate time-point prevalence and risk factors of relapse. Methods: We searched PubMed, Embase, and Cochrane Library databases from their inception to March 30, 2020. Cohorts and post-hoc studies were included ...

    • Peng He, Jin-Ping Hu, Xiu-Juan Tian, Li-Jie He, Shi-Ren Sun, Chen Huang
    • 2021
  7. Nov 2, 2020 · Recurrent or persistent ANCA patterns are associated with a higher risk of clinical relapse. A recurrent ANCA pattern was associated with worsening renal function in anti‐MPO‐associated vasculitis. Go to: Introduction.

  8. Aug 1, 2013 · Because most patients with ANCA-associated vasculitis eventually have a relapse, the duration of treatment-induced remissions, the severity of relapses, and cumulative treatment-related toxic...

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