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Jones, Corbin. Professor. cdjones@email.unc.edu. 3159 Genome Sciences Building. (919) 962-4443 (office) Lab Website. Adaptations are central to the study of evolution. Thus it is surprising that we know so little about the molecular basis of adaptive evolution. The goal of my research is to identify, clone, and characterize the evolution of ...
How important are changes in gene regulation versus amino acid expression to adaptation? In the Corbin Jones lab, we take an integrative and interdisciplinary approach to getting the answers we need. Through the use of genetic analyses of complex adaptive traits, population-scale studies of nucleotide variation, and computational and ...
- Adaptations and Other Interspecific Differences in Drosophila
- Molecular Evolution and Population Genetics of New Genes
- Evolutionary Analysis of QTL and Genomic Data
The tools of modern biology have made dissecting the molecular genetics of adaptation possible, especially in Drosophila. Currently, I am using molecular markers and QTL mapping techniques to precisely map regions harboring adaptive alleles. Candidate genes with changes in expression are identified through microarray and other expression studies. C...
Periodically new genes must arise. We know little about the mechanisms, frequency, or patterns underlying these events. In collaboration with Dr. David Begun, I am identifying these new genes. One intriguing candidate we have already identified is a retrotransposed Alcohol Dehydrogenase (Adh) “pseudogene” in D. guanche, D. madeirensis, and D. subob...
I also work on theoretical and statistical methods related to evolutionary genetics and genomics. This research falls into three areas: (i) estimating the number of genes underlying a quantitative trait from mapping data, (ii) looking at spatial patterns of DNA sequence evolution, and (iii) developing methods for detecting genetic changes due to na...
Corbin is an Associate Professor in the Biology Department of the University of North Carolina as well as an Associate Professor of the Carolina Center for Genome Sciences (CCGS). He is also a Faculty Director of the UNC High-Throughput Sequencing Facility.
The goal of Dr. Corbin Jones’ research is to identify, clone, and characterize the evolution of genes underlying natural adaptations in order to determine the types of genes involved, how many and what types of genetic changes occurred, and the evolutionary history of these changes.
Jul 21, 2015 · Professor of Biology and Genetics. Core Faculty. Research Areas: Bioinformatics, Comparative Genomics and Molecular Evolution, Statistical and Populational Genetics. Research Interests: Developing novel computational approaches for comparative analysis of genomics data. Phone: 919-962-4443.
Corbin Jones, PhD, is a UNC Lineberger Comprehensive Cancer Center member researching the evolution of genes underlying natural adaptations.
