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  1. The skin is often thickened, dry, and scaly, as in simple myxedema (hypothyroidism), sometimes with a brownish hue. After puberty, myxedematous skin changes often regress and leave a coarse wrinkling which, especially on the forehead, contributes much to the typical appearance of cretins.

  2. Nov 17, 2023 · Hyperkeratosis is a condition that causes thick, rough patches of skin. There are many different types of hyperkeratosis. Treatments can help manage most symptoms.

  3. Jan 1, 2011 · The skin changes mentioned are particularly more pronounced among congenital, myxœdematous, athyroids than among cretins; among the latter, more pronounced among dwarf cretins with thyroid atrophy than among cretins with goitre. The same is true of changes to the nails.

    • John Dennison, Charles Oxnard, Peter Obendorf
    • 2012
  4. Mucinosis, or myxomatous change, is the deposition of fine, granular and stringy basophilic material into structures or layers within the skin, within the dermis (eg dermal mucinosis), epidermis (eg small foci seen associated with squamous cell carcinomas, basal cell carcinomas) or within skin structures such as hair follicles (eg follicular ...

  5. Apr 2, 2021 · After a brief description of skin pigmentation and skin conditions showing abnormal pigmentation accompanied by aging, this review covers the association between each of the mechanisms implicated in skin aging and skin hyperpigmentation or hypopigmentation to provide a basis for their possible relationship. Figure 1.

    • Ai-Young Lee
    • 10.3390/ijms22073727
    • 2021
    • Int J Mol Sci. 2021 Apr; 22(7): 3727.
  6. The epidermis has three main types of cell: Keratinocytes (skin cells) Melanocytes (pigment -producing cells) Langerhans cells (immune cells). Special stains are often required to tell the difference between melanocytes and Langerhans cells. The Merkel cell is a fourth, less visible, epidermal cell.

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  8. What are cutaneous markers of internal malignancy? Skin changes may be the first sign of an internal problem including a visceral malignancy.

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