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  1. Jan 5, 2021 · Diabetes insipidus (DI) is a disorder of water balance characterized by polyuria and polydipsia. It can occur at any age, and the reported prevalence is approximately 1:25,000. It can occur due to genetic (10%) and acquired (90%) causes that affect the secretion or action of arginine vasopressin (AVP) or antidiuretic hormone (ADH) [1].

    • Gagan Priya, Sanjay Kalra, Arundhati Dasgupta, Emmy Grewal
    • 10.7759/cureus.12498
    • 2021
    • Cureus. 2021 Jan; 13(1): e12498.
  2. A. Shock: Inadequate tissue perfusion to vital organs that typically manifests itself as respiratory failure, renal failure, altered mental status, DIC Decreased tissue perfusion leads to decreased delivery of vital oxygen/nutrients and energy to cells. This leads to eventual cell necrosis and acidosis and if left untreated can

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  3. Feb 8, 2023 · The major symptoms of arginine vasopressin deficiency (AVP-D), previously called central diabetes insipidus [1], are polyuria, nocturia, and polydipsia due to the concentrating defect. Treatment of this disorder is primarily aimed at decreasing the urine output, usually by increasing the activity of antidiuretic hormone (ADH, also known as ...

  4. Feb 23, 2021 · Introduction and background. Diabetes insipidus (DI) is a rare disorder, affecting roughly 1 in 25,000 people or about 0.004% of the global population [].Due to the rare occurrence in the population, the various forms of DI can be relatively neglected in medical education as well as in a research setting for improving clinical management [].

    • Cody M Mutter, Trevor Smith, Olivia Menze, Mariah Zakharia, Hoang Nguyen
    • 10.7759/cureus.13523
    • 2021
    • Cureus. 2021 Feb; 13(2): e13523.
  5. diabetes insipidus (FIGURE 1): • Inadequate release of antidiuretic hor-mone (ADH, also called vasopressin) from the hypothalamus (central diabetes insipidus) and • Inadequate response of the kidney to ADH (nephrogenic diabetes insipidus). The distinction is essential, since the treatment is different for the two causes, and is

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    • Amgad N Makaryus, Samy I McFarlane
    • 7
    • 2006
  6. Nephrogenic diabetes insipidus happens when your kidneys don’t use antidiuretic hormone (ADH, or vasopressin) properly. Specific causes include: Certain medications, such as lithium and tetracycline. Low levels of potassium in your blood (hypokalemia). High levels of calcium in your blood (hypercalcemia).

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  8. Apr 5, 2023 · Urine test. Testing urine to see if it contains too much water can be helpful in identifying diabetes insipidus. Blood tests. Checking the levels of certain substances in the blood, such as sodium, potassium and calcium, can help with a diagnosis and may be useful in identifying the type of diabetes insipidus. Magnetic resonance imaging (MRI).

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