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Eli Lilly’s Mounjaro, cleared for type 2 diabetes and awaiting FDA approval for weight loss, targets both GLP-1 and a hormone called GIP, and has produced weight loss of 21 to 23%.
- Overview
- What is Lipozene?
- Pros and cons at a glance
- Lipozene for weight loss
- Does Lipozene work?
- Who is Lipozene for?
- Is it safe?
- Benefits
- Reviews and reputation
- Side effects and risks
•Definition
•Pros and cons
•How it works
•Effectiveness
•Who is it for?
•Is it safe?
Lipozene is a branded dietary weight loss supplement that contains glucomannan as an active ingredient. Glucomannan is a fiber from the root of the konjac plant, Amorphophallus konjac.
Glucomannan is a soluble fiber that absorbs many times its weight in water. Because of this, konjac products are popular thickeners in some foods.
The konjac root and its compounds are popular weight loss aids because of this fiber and its ability to absorb water.
Learn more about the benefits of konjac.
Pros
•may enable weight loss •may prevent a person from overeating •may reduce the absorption of fat •may work as a prebiotic, increasing healthy bacteria in the intestines •is additive-free •is laxative-free •is stimulant-free •may reduce levels of glucose •may reduce cholesterol •may reduce fats in the blood •may lower blood pressure
Cons
•only yields mild, inconsistent weight loss in research studies •is unsuitable for vegetarians or vegans •may reduce the effectiveness of certain medications •may cause stomach discomfort, nausea, diarrhea, and constipation •there is a risk of choking Was this helpful?
Glucomannan primarily encourages weight loss through its ability to rapidly absorb water from the upper gastrointestinal tract, increase in size, and form a gel in the stomach. This makes people feel full, and they may eat less as a result.
However, the authors highlight that scientific data proving its beneficial effect on weight loss is inconsistent and that more research is necessary.
Other research shows that viscous soluble fiber, which includes glucomannan, is more likely to encourage satiety than nonviscous types. This is because it delays the processes that empty the stomach, which keeps food in the stomach for longer and slows down digestion and nutrient absorption.
Viscous soluble fiber can also increase the level of short-chain fatty acids (SCFAs) in the body, which can regulate the production of peptides that regulate the appetite. This can also increase a person’s satiety and reduce the amount of food they eat.
Typically, the effectiveness of Lipozene for weight loss is mild. A 2020 study suggests that glucomannan supplements may be effective for people who have obesity. However, there are conflicting reports about its effectiveness.
However, these effects may not apply to everyone. According to a 2019 study, glucomannan did not appear to be more effective than placebo treatment in reducing the body mass index (BMI) of children with overweight and obesity.
The study included 96 participants aged 6–17 years who received glucomannan and maltodextrin supplements for 12 weeks. While glucomannan did not affect BMI scores, it did lower total and low-density lipoprotein cholesterol (LDL), also known as “bad” cholesterol.
Additionally, an older 2013 study on adults with obesity suggests glucomannan does not promote weight loss, alter body composition, or change feelings of hunger or fullness.
For some people, these mixed results may be enough to justify taking Lipozene to boost their diet and weight loss goals. Others may feel these do not justify the cost or potential side effects.
Learn more about the effectiveness of weight loss pills.
Lipozene may be suitable for those who wish to lose weight by reducing their calorie intake.
It may also suit people who want to try a low calorie weight loss pill that uses natural active ingredients. However, Lipozene contains gelatin, meaning it is unsuitable for vegetarians or vegans.
In a 2020 study, researchers found that another glucomannan weight loss brand, PGX, had weight loss benefits in people with overweight and obesity. However, results are inconclusive, and there is little data on how long the weight loss effects may last.
Other people who Lipozene may not be suitable for include those with diabetes. This is because it can block the absorption of some diabetes medications. It can also lower blood glucose, making it potentially unsuitable for people who take medication to lower blood glucose.
Additionally, those who have difficulty swallowing tablets or capsules may wish to avoid Lipozene.
A person needs to always consult a doctor before trying Lipozene to ensure it is safe for them to take.
The active ingredient in Lipozene, glucomannan, is typically safe to consume in amounts of up to 3 grams (g) a day. This is less than the company suggests, which recommends people take up to 4.5 g a day.
Research states that doses higher than 3 g may cause digestive discomfort.
However, it is important for a person to stay well hydrated when taking glucomannan products because it can absorb up to 200 times its weight in water.
Additionally, glucomannan capsules may be safer than powders. As a very absorbent substance, glucomannan can expand before it reaches the stomach, increasing a person’s risk of choking or creating a blockage in their digestive system.
The benefits of glucomannan relate to its specific type of soluble, fermentable dietary fiber.
A 2019 review notes that glucomannan fiber may help:
•reduce levels of glucose
•reduce cholesterol
•reduce fats in the blood
•lower blood pressure
Lipozene has a D+ rating on Better Business Bureau (BBB) but does not hold the platform’s accreditation. It has no reviews and has closed 20 complaints in the past 3 years.
Lipozene.com is registered with Trustpilot, where it has an average rating of 2.5 out of 5 stars based on five reviews.
Reviewers claim that the product does not work and the website does not provide accurate information. Buyers also did not like that they could only buy the supplement on subscription, and some had problems canceling the auto-renewal.
However, one customer wrote that it helped to reduce their cravings, although it did not help them lose weight.
Lipozene failed Medical News Today‘s thorough vetting process. This is because of limited scientific evidence proving the efficacy of its active ingredient, glucomannan, and safety concerns, including obstructions of the bowel and esophagus.
Additionally, the company does not consistently use the required Food and Drug Administration (FDA) disclaimer when making claims about the health benefits of its products. It also does not provide full dosage information for all of the ingredients in its products.
Most people tolerate glucomannan well. However, some people may be more sensitive to soluble fibers, and mild reactions in the digestive system may occur.
Mild side effects from taking glucomannan may include:
•stomach pain
•gas
•constipation
•diarrhea
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Oct 3, 2022 · The weight loss supplement Lipozene claims to cause fast weight loss. This article reviews what it is, whether it works, and its side effects.
- Some people may experience changes in bowel movements after taking Lipozene. This is because Lipozene contains glucomannan, a type of fiber that ha...
- The active ingredient in Lipozene is glucomannan, a type of dietary fiber derived from the roots of the konjac plant (1).
- According to the manufacturer, Lipozene does not contain any caffeine.
- Some studies suggest that glucomannan, the active ingredient in Lipozene, could potentially support short-term weight loss. However, the research i...
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Nov 8, 2023 · The FDA has approved Zepbound, an injectable weight loss drug from Eli Lilly that helped people lose up to 52 lbs in 16 months during clinical trials.
