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  1. 1. a. : the quality or state of being changeable : mutability. b. : natural change or mutation visible in nature or in human affairs. 2. a. : a favorable or unfavorable event or situation that occurs by chance : a fluctuation of state or condition. the vicissitudes of daily life.

  2. Losing a pet, crashing the car, being called in for jury duty: these are examples of vicissitudes — chapters in one's life that one would rather avoid but must get through. Some lives have more vicissitudes than others, to be sure, but no life is without events that test and challenge us.

  3. a change or variation occurring in the course of something. interchange or alternation, as of states or things. vicissitudes, successive, alternating, or changing phases or conditions, as of life or fortune; ups and downs: They remained friends through the vicissitudes of 40 years.

  4. Definition of Vicissitude. a negative change in circumstances or fortunes. Examples of Vicissitude in a sentence. The parental vicissitude I currently have is trying to pay child support for six children. 🔊. My vicissitude in college was tackling seven classes and a job. 🔊

  5. A complete guide to the word "VICISSITUDE": definitions, pronunciations, synonyms, grammar insights, collocations, examples, and translations.

  6. As already observed, the vicissitudes of general economic equilibrium theory are a good example of the spread of the mathematical modeling approach.

  7. We will examine the definition of the word vicissitude, where it came from and some examples of its use in sentences. Vicissitude means a change of ones fortune, a condition of constant change, a series of alternation, the unpredictable and changeable quality of life.

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