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    • A resurgence of COVID-19

      • Paxlovid rebound describes a resurgence of COVID-19 after you finish taking the antiviral drug combination known as Paxlovid. People with Paxlovid rebound don't always feel sick, but they could spread COVID-19 to others. What is Paxlovid rebound? Paxlovid rebound typically happens within a week after you've taken Paxlovid to treat COVID-19.
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  2. May 9, 2024 · What is Paxlovid rebound? Paxlovid rebound typically happens within a week after you've taken Paxlovid to treat COVID-19. With Paxlovid rebound, either your COVID-19 symptoms return or you test positive after testing negative. Sometimes it's both. Paxlovid rebound is usually milder than the initial illness. The main concern is spreading the ...

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    • kathy.katella-cofrancesco@yale.edu
    • What, exactly, is COVID rebound? COVID rebound is defined as a recurrence of COVID symptoms and/or receiving a positive COVID test after having the disease and then testing negative.
    • What do you need to know about Paxlovid? The drug, available by prescription from health care providers and some pharmacists, is available to everyone ages 12 and older (weighing at least 88 pounds) who has mild-to-moderate disease and is at high risk for severe disease.
    • Does Paxlovid cause COVID rebound? So far, researchers say there is no strong evidence of that. The CDC notes in a health advisory that “a brief return of symptoms may be part of the natural history of SARS-CoV-2 infection in some persons, independent of treatment with Paxlovid and regardless of vaccination status.”
    • What causes COVID rebound? Scientists are still studying the phenomenon. In the meantime, researchers are focusing on the effects of longer treatment durations, longer isolation periods, and other ways of managing the problem, Dr. Roberts adds.
  3. Aug 8, 2022 · The CDC defines Paxlovid rebound as when a patient who, after receiving a full five-day course of treatment, either has a reemergence of COVID symptoms or tests positive after a previous,...

  4. Sep 26, 2023 · The theory behind Paxlovid rebound is that the treatment is so effective at suppressing the virus that the immune system does not ramp up its cellular and antibody...

    • Dani Blum
  5. Feb 20, 2024 · Does Paxlovid cause rebound symptoms? A CDC review of COVID rebound studies found “no consistent association between treatment and rebound.” Paxlovid does not directly cause symptoms to return; in fact, only about 1 in 5 people who take Paxlovid experience rebound , and many of those are asymptomatic.

  6. Paxlovid (nirmatrelvir tablets; ritonavir tablets) is a prescription oral antiviral drug that reduces the risk of hospitalization and death for patients with mild-to-moderate COVID-19 who are at risk of disease progression and severe illness (1).

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