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  1. www.ncbi.nlm.nih.gov › pmc › articlesTreatment of Relapses in ANCA-Associated Vasculitis

    Jul 5, 2019 · Diagnostic and therapeutic advances have changed the paradigm of ANCA associated vasculitis from a fatal diagnosis to a chronic relapsing disease. Avoiding long-term treatment toxicity and preventing, detecting, and treating relapses early are key clinical strategies to reduce organ damage and improve quality of life.

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  3. www.mayoclinic.org › medical-professionalsUpdate on the management of ANCA-associated vasculitis

    Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis comprises three syndromes, all with frequent respiratory manifestations. Studies indicate that ANCA specificity is more important for prognosis, relapse risk, response to therapy and outcomes than the specific diagnosis.

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  5. www.ncbi.nlm.nih.gov › pmc › articlesUpdate in the Management of ANCA-Associated Vasculitis ...

    Apr 8, 2021 · The first Maintenance of Remission using Rituximab in Systemic ANCA-Associated Vasculitis (MAINRITSAN) study included newly diagnosed, severe relapsing GPA or MPA, or renal-limited ANCA-associated vasculitis.

    • Karla N. Samman, Carolyn Ross, Christian Pagnoux, Jean-Paul Makhzoum
    • 10.1155/2021/5534851
    • 2021
    • Int J Rheumatol. 2021; 2021: 5534851.

  6. www.ncbi.nlm.nih.gov › pmc › articlesANCA-Associated Vasculitis: An Update - PMC

    Apr 1, 2021 · Patients with MPO-ANCA had a low relapse rate to start that remained low (pre- and post-ESRD relapse rates of 0.06 and 0.04 episodes/person-year, respectively; p = 0.47). Thus early withdrawal of immunosuppression should be considered in patients with ESRD due to ANCA-associated glomerulonephritis, especially those with MPO-ANCA.

    • Salem Almaani, Lynn A. Fussner, Sergey Brodsky, Alexa S. Meara, David Jayne
    • 10.3390/jcm10071446
    • 2021
    • J Clin Med. 2021 Apr; 10(7): 1446.

  7. academic.oup.com › rheumatology › articlePrevalence and risk factors of relapse in patients with ANCA ...

    Nov 28, 2020 · Clinical relapses are common in patients with ANCA-associated vasculitis (AAV). The aim of this systematic review was to estimate time-point prevalence and risk factors of relapse. Methods. We searched PubMed, Embase, and Cochrane Library databases from their inception to March 30, 2020.

    • Peng He, Jin-Ping Hu, Xiu-Juan Tian, Li-Jie He, Shi-Ren Sun, Chen Huang
    • 2021

  8. ard.bmj.com › content › 83/1/30EULAR recommendations for the management of ANCA-associated ...

    The clinical disease type (GPA vs MPA), ANCA serotype (PR3-ANCA vs MPO-ANCA) and ANCA status (positive vs negative) have all been associated with the risk of relapse.

  9. www.nejm.org › doi › fullEfficacy of Remission-Induction Regimens for ANCA-Associated ...

    Aug 1, 2013 · Because most patients with ANCA-associated vasculitis eventually have a relapse, the duration of treatment-induced remissions, the severity of relapses, and cumulative treatment-related...

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