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Aug 30, 2021 · Analysis of hemolysis genes showed that among 100 UPEC isolates, hlyD was the most frequent virulence gene, detected in 95% of the isolates, followed by hlyA with 50%, hlyB with 43%, and hlyC with 23% (Figure 1 (Fig. 1)). The PCR products were evaluated on 2% agarose gel.
Nov 12, 2019 · Macrophage elimination or GM-CSF neutralization protected against acute kidney injury in mice, and increased GM-CSF was detected in urine of patients infected by hlyA -positive UPEC. In...
- Changying Wang, Qianqian Li, Junqiang Lv, Xuan Sun, Yang Cao, Kaiyuan Yu, Chunhui Miao, Zhi-Song Zha...
- 2020
May 11, 2023 · Interestingly, a clinical study has reported that whereas 37.6% of UPEC isolated from first-time UTI patients express the hlyA gene, this number jumped to 48.2% in patients experiencing recurring UTI, suggesting that HlyA might contribute to bacterial persistence in the bladder and recurrent UTIs .
Jul 28, 2020 · The UPEC HlyA, a PFT, causes mitochondrial fragmentation and loss of mitochondrial membrane potential, which finally results in mitochondrial dysfunction in sertoli cells of...
- Vivek Verma, Parveen Kumar, Surbhi Gupta, Sonal Yadav, Rakesh Singh Dhanda, Henrik Thorlacius, Manis...
- 2020
Jul 26, 2021 · Escherichia coli Alpha-Hemolysin HlyA Induces Host Cell Polarity Changes, Epithelial Barrier Dysfunction and Cell Detachment in Human Colon Carcinoma Caco-2 Cell Model via PTEN-Dependent Dysregulation of Cell Junctions - PMC. Journal List. Toxins (Basel) PMC8402498. As a library, NLM provides access to scientific literature.
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Sep 1, 2018 · Application of hlyD qPCR to efficiently detect and quantitate hemolytic UPEC in urine samples from infected mice. Abstract. Uropathogenic Escherichia coli (UPEC) cause the majority of community-acquired urinary tract infections (UTIs).
