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  1. César Milstein was awarded the 1984 Nobel Prize in Physiology or Medicine jointly with his former postdoctoral fellow Georges J. F. Köhler (AAI '85) and theoretician Niels Jerne (AAI '73). Milstein and Köhler won the prize for developing the hybridoma method of producing monoclonal antibodies.

  2. Jun 1, 2002 · In memoriam: César Milstein, who with the late Georges Köhler invented monoclonal antibodies, died on 24 March 2002. Their invention sprang from basic research on antibody diversity and...

  3. Apr 25, 2002 · César Milstein began to study antibody diversity at a time when almost nothing was known about its molecular and genetic basis. As a logical step in that work, with Georges Köhler he devised...

  4. May 1, 2002 · Cesar Milstein, one of the key figures in the development of monoclonal antibodies, died on 24 March 2002 at the age of 74. Together with Georges Köhler, Milstein reported a hybridoma technique...

  5. He focused on antibodies, the proteins produced by mature B lymphocytes (plasma cells) as part of the immune response. Milstein used myeloma cells, cancerous forms of plasma cells that multiply indefinitely, to study somatic hypermutation and the mechanism by which antibody diversity is generated.

  6. Milstein, César ( 19272002 ), molecular biologist and immunologist, was born on 8 October 1927 in Bahía Blanca, a provincial town in Argentina, the second of three sons of Lázaro Milstein, a salesman who had travelled to Argentina at the age of fourteen as a Jewish immigrant from the Ukraine before the First World War, and his wife, Máxima, als...

  7. Documentary. César Milstein describes how, while sitting in a meeting at his work at the MRC Laboratory of Molecular Biology, they were suddenly interrupted and he was informed that he had been awarded the Nobel Prize in Physiology or Medicine 1984. To cite this section. MLA style: César Milstein – Documentary.

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