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  1. May 6, 2021 · In the current report, Pfizer-BioNTech and Moderna vaccine products were equally represented, and approximately one half of the patients were aged ≥75 years, providing evidence of real-world effectiveness of both vaccines against an important measure of severe COVID-19 in older adults.

    • Mark W. Tenforde, Samantha M. Olson, Wesley H. Self, H. Keipp Talbot, Christopher J. Lindsell, Jay S...
    • 2021
    • 065208055
    • kathy.katella-cofrancesco@yale.edu
    • Why would another COVID vaccination help? The updated vaccines are not expected to prevent all cases of COVID, including those causing mild illness; rather, their aim is to reduce severe illness, hospitalization, and death from infection.
    • How is the updated COVID vaccine different from the previous one? The bivalent booster, which is no longer available, was introduced in the fall of 2022.
    • Why isn’t the new COVID vaccine considered a booster? The FDA is calling the new shots “updated vaccines” in anticipation of needing to provide updated formulas annually, similar to the flu shot, which changes each year.
    • How safe is the updated COVID vaccine? COVID vaccines are safe and effective, according to the CDC. The safety of COVID vaccines has been rigorously monitored and evaluated since their emergency use authorization (EUA) in December 2020.
  2. Nov 3, 2023 · In December 2020, the Pfizer-BioNTech COVID-19 vaccine two-dose series was found to be both safe and 91% to 95% effective in preventing COVID-19 infection in people age 18 and older. This data helped predict how well the vaccines would work for younger people.

  3. Sep 15, 2023 · Pfizer’s BNT162b2 mRNA Covid-19 vaccine was the first vaccine against the novel coronavirus (COVID-19) approved for distribution in the United States. The approval came as an emergency use authorization on December 11, 2020, after clinical trials showed the vaccine was 95% effective in preventing COVID-19. Getty Images.

  4. Mar 11, 2021 · Vaccine effectiveness was at least 97% against symptomatic COVID-19 cases, hospitalizations, severe and critical hospitalizations, and deaths. Furthermore, the analysis found a vaccine effectiveness of 94% against asymptomatic SARS-CoV-2 infections. For all outcomes, vaccine effectiveness was measured from two weeks after the second dose.

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