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Apr 12, 2022 · The orthonairovirus phylogenetic tree (top) was constructed based on a concatenated mafft-alignment of the three proteins encoded by the three orthonairovirus genome segments [nucleoprotein (S segment), glycoprotein precursor (M segment), large protein (L segment)], using the E-INS-i algorithm. The phylogeny was inferred using IQtree and the LG ...
Abstract: Dugbe orthonairovirus (DUGV) is a tick-borne arbovirus within the order Bunyavirales. DUGV was first isolated in Nigeria, but virus isolations in ten further African countries indicate that
Aug 25, 2022 · The full-length genome was determined by RT-PCR and RACE. Genomic architecture of MHMV shares typical features with orthonairoviruses. Phylogenetic analyses suggested that MHMV is clustered into the Nairobi sheep disease (NSD) genogroup of the genus Orthonairovirus and is closely related to the Hazara virus. The RdRp, GPC, and N protein of MHMV ...
Aug 25, 2020 · Members of the family Nairoviridae produce enveloped virions with three single-stranded RNA segments comprising 17.1 to 22.8 kb in total. These viruses are maintained in arthropods and transmitted by ticks to mammals or birds. Crimean-Congo hemorrhagic fever virus is tick-borne and is endemic in most of Asia, Africa, Southern and Eastern Europe ...
A novel orthonairovirus named Dadong virus (DDV) was isolated from Haemaphysalis concinna ticks in the Changbai Mountain region on the China-North Korea … Emerging pathogenic tick-borne viruses (TBVs) have attracted a great deal of attention due to their significant impact on human and animal health.
Oct 5, 2017 · Furthermore, the analysis suggests that Burana virus and Tamdy virus are both members of the species Burana orthonairovirus (proposed to be renamed “Tamdy orthonairovirus”), Caspiy virus is a member of the species Hughes orthonairovirus, Uzun-Agach virus is a member of the species Keterah orthonairovirus, and Geran virus is a member of the ...
Jul 13, 2021 · Antibody cross-reactivities between related viruses are common diagnostic challenges, resulting in reduced diagnostic specificities and sensitivities. In this study, antibody cross-reactions between neglected members of the genus Orthonairovirus -Hazara (HAZV), Dugbe (DUGV), and Nairobi sheep disease orthonairovirus (NSDV)-were investigated.
