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  1. The lipid envelope of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an essential component of the virus; however, its molecular composition is undetermined. Addressing this knowledge gap could support the design of antiviral agents as well as further our understanding of viral-host ….

  2. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a β-coronavirus, is the causative agent of the COVID-19 pandemic. Like for other coronaviruses, its particles are composed of four structural proteins: spike (S), envelope (E), membrane (M), and nucleoprotein (N) proteins.

    • Bertrand Boson, Vincent Legros, Bingjie Zhou, Eglantine Siret, Cyrille Mathieu, François-Loïc Cosset...
    • 2021
  3. Dec 12, 2021 · The SARS-CoV-2 envelope protein (E-protein) is a 10 kDa protein with an N-terminal transmembrane domain and a C-terminal cytoplasmic tail . In SARS-CoV, E-protein mediates the budding and release of progeny viruses and also activates the host inflammasome.

    • Jahangir Emrani, Maryam Ahmed, Liesl Jeffers-Francis, John C. Teleha, Nathan Mowa, Robert H. Newman,...
    • 10.1016/j.ijbiomac.2021.10.172
    • 2021
    • 2021/12/12
  4. May 30, 2020 · Abstract. The Coronavirus Disease 2019 (COVID-19) is a new viral infection caused by the severe acute respiratory coronavirus 2 (SARS-CoV-2). Genomic analyses have revealed that SARS-CoV-2 is related to Pangolin and Bat coronaviruses.

    • Martina Bianchi, Domenico Benvenuto, Marta Giovanetti, Silvia Angeletti, Massimo Ciccozzi, Stefano P...
    • 10.1155/2020/4389089
    • 2020
    • Biomed Res Int. 2020; 2020: 4389089.
  5. Oct 23, 2020 · SARS-CoV-2 is an enveloped β-coronavirus, with a genetic sequence very similar to SARS-CoV-1 (80%) and bat coronavirus RaTG13 (96.2%). 2 The viral envelope is coated by spike (S) glycoprotein, envelope (E), and membrane (M) proteins ( fig 1 ). Host cell binding and entry are mediated by the S protein.

  6. Sep 17, 2021 · Coronaviruses are enveloped viruses that possess a positive-sense single-stranded RNA genome 26–32 kb in length 1. Coronaviruses belong to the Coronaviridae subfamily Orthocoronavirinae.

    • Haitao Yang, Zihe Rao
    • 2021
  7. Nov 11, 2020 · An essential protein of the SARS-CoV-2 virus, the envelope protein E, forms a homopentameric cation channel that is important for virus pathogenicity. Here we report a 2.1-Å structure and the...

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