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Jun 30, 2002 · Erwin Chargaff, whose research into the chemical composition of DNA helped lay the groundwork for James Watson and Francis Crick's discovery of its double-helix structure -- the pivotal finding...
His two main discoveries, (i) that in any double-stranded DNA the number of guanine units equals thenumber of cytosine units and the number of adenine units equals the number ofthymine units and (ii) that the composition of DNA varies from one species toanother, are now known as Chargaff's Rules.
One other key piece of information related to the structure of DNA came from Austrian biochemist Erwin Chargaff. Chargaff analyzed the DNA of different species, determining its composition of A, T, C, and G bases. He made several key observations: A, T, C, and G were not found in equal quantities (as some models at the time would have predicted)
In heredity: Structure and composition of DNA. …it was found by biochemist Erwin Chargaff that the amount of A is always equal to T, and the amount of G is always equal to C. Read More.
Erwin Chargaff was one of a handful of scientists who expanded on Levene's work by uncovering additional details of the structure of DNA, thus further paving the way for Watson and Crick.
Health & Medicine. Affiliations. Columbia University. Erwin Chargaff was awarded the National Medal of Science for fundamental chemical and biological studies establishing the basis for modern concepts of the mechanisms of protein synthesis and the genetic role of nucleic acids.
Erwin Chargaff (Czernowitz, August 11, 1905 – New York City, USA, June 20, 2002) was an American biochemist who emigrated to the United States during the Nazi era. Through careful experimentation, Chargaff discovered two rules that helped lead to the discovery of the double helix structure of DNA.
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