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1. www.nejm.org › doi › fullGene Editing for CEP290-Associated Retinal Degeneration

   www.nejm.org › doi › full

   May 6, 2024 · Published May 6, 2024. DOI: 10.1056/NEJMoa2309915. Abstract. Background. CEP290 -associated inherited retinal degeneration causes severe early-onset vision loss due to pathogenic variants in...

2. eurjmedres.biomedcentral.com › articles › 10Comparison of angiographic change in side-branch ostium after ...

   eurjmedres.biomedcentral.com › articles › 10

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   1 day ago · Objectives Data on side-branch (SB) ostial effect after drug-coated balloon (DCB) treatment in the context of de novo coronary bifurcation lesions are limited. We aimed to investigate the angiographic outcomes of SB ostium after DCB treatment compared with drug-eluting stents (DESs) implantation in the main vessel (MV) or optimal medical therapy (OMT) for the treatment of de novo coronary ...

3. www.nejm.org › doi › fullExtending Gene Medicines to All in Need | New England Journal ...

   www.nejm.org › doi › full

   Apr 24, 2024 · Extending Gene Medicines to All in Need. Authors: Joseph M. McCune, M.D., Ph.D., and Hans-Peter Kiem, M.D., Ph.D. Author Info & Affiliations. Published April 24, 2024.

4. www.nature.com › articles › s41591/024/02931-wAPOE4 homozygozity represents a distinct genetic form of ...

   www.nature.com › articles › s41591/024/02931-w

   May 6, 2024 · The study on APOE4 homozygosity indicates a genetic variant of Alzheimer’s disease with early symptom onset and distinct biomarker progression, highlighting the need for specialized treatment ...

5. link.springer.com › journal › 40001Volume 29, issue 1 | European Journal of Medical Research

   link.springer.com › journal › 40001

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   Apr 30, 2024 · Perceptions and engagement of patients with chronic conditions on the use of medical cannabis: a scoping review. Marie-Pascale Pomey. Didier Jutras-Aswad. Pierre Duquette. Review. Open Access. Published: 01 April 2024. Article: 211. Volume 29, issue 1 articles listing for European Journal of Medical Research.

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7. onlinelibrary.wiley.com › doi › 10New York Heart Association functional class and implantable ...

   onlinelibrary.wiley.com › doi › 10

   2 days ago · Introduction. Despite its limitations, the New York Heart Association (NYHA) functional classification remains the most commonly used measure of symptom burden and functional capacity in patients with heart failure in clinical practice. 1, 2 NYHA functional class is associated with morbidity and mortality regardless of left ventricular ejection fraction (LVEF), 3-5 and since it represents a ...

8. www.ahajournals.org › doi › fullReduced Sclerostin Expression in Human Atherosclerotic ...

   www.ahajournals.org › doi › full

   3 days ago · Given the accumulating data regarding the side effects of romosozumab, used to treat osteoporosis at present there is a safety warning from the Food and Drug Administration and the European Medicines Agency to avoid romosozumab treatment of patients with a history of major adverse cardiac events (MACE). 5 In this context, the present finding ...