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The SARS-CoV-2 RNA sequence is approximately 30,000 bases in length, [110] relatively long for a coronavirus—which in turn carry the largest genomes among all RNA families. [111] Its genome consists nearly entirely of protein-coding sequences, a trait shared with other coronaviruses.
Dec 12, 2021 · Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as “the novel coronavirus” due to genome variation relative to previously identified coronaviruses, is a positive sense RNA virus and the etiological agent of COVID-19.
- Jahangir Emrani, Maryam Ahmed, Liesl Jeffers-Francis, John C. Teleha, Nathan Mowa, Robert H. Newman,...
- 10.1016/j.ijbiomac.2021.10.172
- 2021
- 2021/12/12
Oct 6, 2020 · Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute respiratory...
- Ben Hu, Hua Guo, Peng Zhou, Zheng Li Shi
- 2021
Nov 25, 2021 · Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other coronaviruses rely on a cohort of specialized viral proteins to transcribe and replicate their RNA genomes.
- Brandon Malone, Nadya Urakova, Eric J Snijder, Elizabeth A Campbell
- 2021
Jun 24, 2021 · SARS-CoV-2 carries the largest single-stranded RNA genome and is the causal pathogen of the ongoing COVID-19 pandemic. How the SARS-CoV-2 RNA genome is folded in the virion remains unknown.
- Changchang Cao, Zhaokui Cai, Xia Xiao, Jian Rao, Juan Chen, Naijing Hu, Minnan Yang, Xiaorui Xing, Y...
- 2021
Oct 1, 2020 · The genome of SARS-CoV-2 is comprised of a single-stranded positive-sense RNA . The newly sequenced genome of the SARS-CoV-2 was submitted in the NCBI genome database (NC_045512.2) ~29.9 Kb in size . The genetic makeup of SARS-CoV-2 is composed of 13–15 (12 functional) open reading frames (ORFs) containing ~30,000 nucleotides.
Jul 1, 2021 · SARS-CoV-2 is an RNA virus whose success as a pathogen relies on its abilities to repurpose host RNA-binding proteins (RBPs) and to evade antiviral RBPs. To uncover the SARS-CoV-2 RNA interactome, we here develop a robust ribonucleoprotein (RNP) capture protocol and identify 109 host factors that di ….
