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Aug 18, 2023 · Effect of SARS-CoV-2 on Extrapulmonary Organ Systems. Although the respiratory system is the principal target for SARS-CoV-2, other major organ systems such as the gastrointestinal tract (GI), hepatobiliary, cardiovascular, renal, and central nervous systems may also be affected.
Apr 15, 2024 · Romano, M. et al. A structural view of SARS-CoV-2 RNA replication machinery: RNA synthesis, proofreading and final capping. Cells 9, 1267 (2020).
Apr 19, 2023 · So far, a few small-molecule antiviral drugs (nirmatrelvir–ritonavir, remdesivir and molnupiravir) and 11 monoclonal antibodies have been marketed for the treatment of COVID-19, mostly requiring...
The elimination of SARS-Cov2 requires a coordinated response which should include: the cytokine release, Th1/2 immunity and synthesis of neutralizing antibodies by LB/plasma cells SARS- Cov-2 potential therapeutic targets encompass the following steps: blocking ACE2 receptors (monoclonal antibodies); TMPRSS inhibition which prevents endosomal ...
Sep 17, 2021 · 51 Altmetric. Metrics. Abstract. The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an unprecedented global health crisis. However, therapeutic...
Dec 20, 2023 · For diagnosing current SARS-CoV-2 infection, the CDC recommends using either a nucleic acid amplification test (NAAT) or an antigen test and using a specimen from the upper respiratory tract (e.g., nasal, nasopharyngeal). There may be a window period of up to 5 days after exposure before viral antigens or nucleic acids can be detected.
