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  1. Overview. HyPhy ( Hy pothesis Testing using Phy logenies) is an open-source software package for the analysis of genetic sequences (in particular the inference of natural selection) using techniques in phylogenetics, molecular evolution, and machine learning.

  2. Aug 27, 2019 · HYpothesis testing using PHYlogenies (HyPhy) is a scriptable, open-source package for fitting a broad range of evolutionary models to multiple sequence alignments, and for conducting subsequent parameter estimation and hypothesis testing, primarily in the maximum likelihood statistical framework.

    • Sergei L Kosakovsky Pond, Art F Y Poon, Ryan Velazquez, Steven Weaver, N Lance Hepler, Ben Murrell, ...
    • 10.1093/molbev/msz197
    • 2020
    • Mol Biol Evol. 2020 Jan; 37(1): 295-299.
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  4. HyPhy is most commonly used for characterizing the evolutionary process, in particular: Detecting signatures of selection. Estimating evolutionary rates. Comparing different evolutionary models. Fitting custom models to sequence alignments. Characterizing selective pressures.

  5. Tutorials. Video tutorials for DataMonkey.org and HyPhy. Using HyPhy as a Command Line Tool. Using HyPhy Interactive Command Line Prompt to Detect Selection. Using HyPhy-GUI to Detect Selection. Labeling branches with phylotree. Information, documentation, and news about the HyPhy software package.

  6. HYPHY (/ ˈ h aɪ f aɪ / HY-fy) is a free multiplatform (Mac, Windows and UNIX) computational phylogenetics software package intended to perform maximum likelihood analyses of genetic sequence data and equipped with tools to test various statistical hypotheses.

    • Sergei L Kosakovsky Pond, Art FY Poon, Steven Weaver, N. Lance Hepler, Martin Smith.
    • English
  7. Sep 13, 2023 · Software Description. HyPhy stands for hypothesis testing using phylogenies. It is an open-source software package for the analysis of genetic sequences using techniques in phylogenetics, molecular evolution, and machine learning. It also features a complete graphical user interface (GUI) and a rich scripting language for limitless ...

  8. HyPhy is an open-source software package for the analysis of genetic sequences using techniques in phylogenetics, molecular evolution, and machine learning. It features a complete graphical user interface (GUI) and a rich scripting language for limitless customization of analyses.

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