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Gain-of-function research ( GoF research or GoFR) is medical research that genetically alters an organism in a way that may enhance the biological functions of gene products. This may include an altered pathogenesis, transmissibility, or host range, i.e., the types of hosts that a microorganism can infect. This research is intended to reveal ...
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Jun 21, 2021 · Gain-of-function research is when scientists modify organisms to acquire new abilities or properties, such as making a virus more transmissible or lethal. Learn why this type of research is important, how it is done and what are the controversies around SARS-CoV-2.
Sep 9, 2021 · Learn what gain of function (GoF) research means and how it is done on viruses and other organisms. Find out why GoF research is important, controversial and regulated.
Apr 13, 2015 · TYPES OF GAIN-OF-FUNCTION (GOF) RESEARCH. Subbarao explained that routine virological methods involve experiments that aim to produce a gain of a desired function, such as higher yields for vaccine strains, but often also lead to loss of function, such as loss of the ability for a virus to replicate well, as a consequence.
- Division on Earth, Law
- 2015/04/13
- 2015
Sep 4, 2022 · Gain-of-function research (GOFR) refers to the serial passaging of microorganisms to increase their transmissibility, virulence, immunogenicity, and host tropism by applying selective pressure...
- Neha Mathur
May 8, 2023 · Gain-of-function research is a tool to study how living things operate by changing or adding a function. It can lead to medical advances, such as vaccines and immunotherapies, but also carries some risks of accidental outbreaks.
Nov 1, 2021 · What exactly is gain-of-function research, and is it cause for alarm? Researchers have been modifying viruses for decades—and not always in benign ways.
