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Jun 23, 2023 · Bullous pemphigoid is an autoimmune cutaneous blistering disease characterized by autoantibody deposition at the epithelial basement membrane zone. The disorder most frequently affects older adults and classically presents with generalized, pruritic, urticarial plaques and tense, subepithelial blisters ( picture 1A-D ).
Apr 29, 2024 · Bullous pemphigoid and mucous membrane pemphigoid (MMP) are autoimmune blistering diseases that most commonly arise in older adults (picture 1A-F). These disorders are characterized by subepithelial blister formation and the deposition of immunoglobulins and complement within the epidermal and/or mucosal basement membrane zone.
Bullous pemphigoid and mucous membrane pemphigoid (MMP) are autoimmune blistering diseases that most commonly arise in older adults ( picture 1A-F ). These disorders are characterized by subepithelial blister formation and the deposition of immunoglobulins and complement within the epidermal and/or mucosal basement membrane zone.
Mar 2, 2023 · Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering disorder, representing 80% of subepidermal immunobullous cases. Bullous pemphigoid most commonly affects elderly patients between the ages of 60 to 80 years.
- Dana Baigrie, Vinod Nookala
- 2023/03/02
- Overview
- Symptoms
- Causes
Bullous pemphigoid (BUL-us PEM-fih-goid) is a rare skin condition that causes large, fluid-filled blisters. They develop on areas of skin that often flex — such as the lower abdomen, upper thighs or armpits. Bullous pemphigoid is most common in older adults. Bullous pemphigoid occurs when your immune system attacks a thin layer of tissue below your...
The signs and symptoms of bullous pemphigoid may include: 1. Itching skin, weeks or months before blisters form 2. Large blisters that don't easily rupture when touched, often along creases or folds in the skin 3. Skin around the blisters that is normal, reddish or darker than normal 4. Eczema or a hive-like rash 5. Small blisters or sores in the m...
The blisters occur because of a malfunction in your immune system. Your body's immune system normally produces antibodies to fight bacteria, viruses or other potentially harmful foreign substances. For reasons that are not clear, the body may develop an antibody to a particular tissue in your body. In bullous pemphigoid, the immune system produces ...
Bullous pemphigoid is the most common form of autoimmune subepidermal blistering disease. Treatment for bullous pemphigoid is usually needed for several years. In many cases, the pemphigoid eventually completely clears up, and the treatment can be stopped.
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May 13, 2022 · Bullous pemphigoid (bull-us pem-fuh-goyd) is a rare skin condition that causes itchy, hive-like welts or fluid-filled blisters. It may affect a small area of your body or it may be widespread.