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    • Hormonal treatment (ACTH or steroids)

      • Treatment for infantile spasms typically involves hormonal treatment (ACTH or steroids) as the preferred first choice, or Vigabatrin, and antiepileptic medication. Other treatments may be used in some circumstances.
      www.dsau.org › issue-29-down-syndrome-and-infantile-spasms-outcomes-and-impact
  1. Jan 9, 2019 · The objective of this study was to evaluate infantile spasms in children with Down syndrome to assess for efficacy of treatments, presence of treatment lag, and to identify clinical presentation and comorbidities likely to contribute to infantile spasms outcomes in this population.

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    • What Are The Signs and Symptoms of Infantile Spasms?
    • How Often Do Infantile Spasms occur?
    • What Causes Infantile Spasms?

    During an infantile spasm, your baby’s body will stiffen or tense up suddenly and only for a couple of seconds. They may also arch their back, and their arms, legs and/or head may bend forward. Infantile spasms often happen one after another in a cluster with five- to 10-second pauses in between spasms. After a spasm or series of spasms, your baby ...

    A baby can have as many as 100 spasms a day. Each baby is affected differently, so if you notice your baby having spasms — even if it’s once or twice a day — it’s important to talk to their pediatrician as soon as possible.

    There are several causes of infantile spasms. Scientists have listed over 200 different health conditions as possible causes of infantile spasms. But in about one-third of cases, healthcare providers can’t determine the cause. An infantile spasm may happen due to an abnormality in a small portion of your child’s brain or may be due to a more genera...

  3. How are infantile spasms treated? If you suspect that your child has infantile spasms, bring your child to a pediatric neurologist for urgent evaluation There are many treatments available for infantile spasms. Some are more effective than others based on the specific cause of the seizures. The neurologist will tailor the treatment to your child.

  4. Treatment for infantile spasms typically involves hormonal treatment (ACTH or steroids) as the preferred first choice, or Vigabatrin, and antiepileptic medication. Other treatments may be used in some circumstances. It is generally believed that children with Down syndrome and infantile spasms have a better response to treatment and

  5. Sep 22, 2022 · The preferred first-line treatment for ISS consists of either hormone-based monotherapy (AdrenoCorticoTropic Hormone [ACTH] or prednisolone) or a combination of hormone and vigabatrin. Children with tuberous sclerosis complex and those with contraindications against hormone treatment should be treated with vigabatrin.

  6. Sep 1, 2015 · Treatment of infantile spasms has little class I data, but adrenocorticotropic hormone (ACTH), prednisolone and vigabatrin have the best evidence as first-line medications. Other therapies including the ketogenic diet and other anti-epileptics medications may also prove useful in the treatment of infantile spasms.

  7. Jan 9, 2019 · To evaluate infantile spasms in children with Down syndrome including assessment of efficacy of treatments, presence of treatment lag, and to identify risk factors that may predict the occurrence of infantile spasms in this population.

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